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CATH Superfamily 1.10.1740.10

RNA polymerase sigma factor, region 2, helix turn helix motif

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: RNA polymerase sigma factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
 21 Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP)
(11 more)
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
 11 Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS)
(1 more)
Siderophore uptake transmembrane transporter activity GO:0015344
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).
 10 Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of iron ion transport GO:0034756
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 21 Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP) Q9I114 (/IMP)
(11 more)
Regulation of iron ion transport GO:0034756
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 11 Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS) Q9HXB4 (/ISS)
(1 more)
Siderophore transport GO:0015891
The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 10 Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP) Q9I2J2 (/IMP)
Iron ion transport GO:0006826
The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 2 Q4KED5 (/TAS) Q4KED5 (/TAS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 21 Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS) Q9HXB4 (/NAS)
(11 more)