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CATH Superfamily 1.10.1740.10

RNA polymerase sigma factor, region 2, helix turn helix motif

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: RNA polymerase sigma factor PvdS

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
 16 G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) P95425 (/IDA) P95425 (/IDA)
(6 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 13 G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) Q884G0 (/IMP) Q884G0 (/IMP)
(3 more)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
 13 G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) Q884G0 (/IMP) Q884G0 (/IMP)
(3 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 8 G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
 8 G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
 16 G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) P95425 (/IMP) P95425 (/IMP)
(6 more)
Positive regulation of secondary metabolite biosynthetic process GO:1900378
Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
 16 G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) P95425 (/IDA) P95425 (/IDA)
(6 more)
Positive regulation of secondary metabolite biosynthetic process GO:1900378
Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
 16 G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) P95425 (/IMP) P95425 (/IMP)
(6 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 8 G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA)
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
 8 G3XCV1 (/EXP) G3XCV1 (/EXP) G3XCV1 (/EXP) G3XCV1 (/EXP) G3XCV1 (/EXP) G3XCV1 (/EXP) G3XCV1 (/EXP) G3XCV1 (/EXP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 5 Q884G0 (/EXP) Q884G0 (/EXP) Q884G0 (/EXP) Q884G0 (/EXP) Q884G0 (/EXP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 5 Q884G0 (/IEP) Q884G0 (/IEP) Q884G0 (/IEP) Q884G0 (/IEP) Q884G0 (/IEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 13 G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) G3XCV1 (/IMP) Q884G0 (/IMP) Q884G0 (/IMP)
(3 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 8 G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA) G3XCV1 (/IDA)