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CATH Superfamily 1.10.1740.10

RNA polymerase sigma factor, region 2, helix turn helix motif

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 37: 1-deoxy-D-xylulose 5-phosphate reductoisomerase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1-deoxy-D-xylulose-5-phosphate reductoisomerase. [EC: 1.1.1.267]
2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH.
  • The enzyme from several eubacteria, including Escherichia coli, forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.
  • The mechanism has been shown to be a retroaldol/aldol reaction.
 5 B0RW72 Q4USQ4 Q4USQ4 Q8PAV9 Q8PAV9