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CATH Superfamily 1.10.1740.10

RNA polymerase sigma factor, region 2, helix turn helix motif

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22: RNA polymerase sigma factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
 8 P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
 8 P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP) P9WGG9 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
 8 P9WGG9 (/IEP) P9WGG9 (/IEP) P9WGG9 (/IEP) P9WGG9 (/IEP) P9WGG9 (/IEP) P9WGG9 (/IEP) P9WGG9 (/IEP) P9WGG9 (/IEP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.