The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: RNA polymerase sigma factor FliA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
177 P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI) P0A2E8 (/IPI)
(167 more)
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
48 Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS)
(38 more)
Antisigma factor binding GO:0045152
Interacting selectively and non-covalently with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
1 O67268 (/IPI)
Disordered domain specific binding GO:0097718
Interacting selectively and non-covalently with a disordered domain of a protein.
1 O67268 (/IPI)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-templated transcription, initiation GO:0006352
Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
48 Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS) Q884V7 (/ISS)
(38 more)
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
8 P29248 (/IMP) P29248 (/IMP) P29248 (/IMP) P29248 (/IMP) P29248 (/IMP) P29248 (/IMP) P29248 (/IMP) P29248 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
7 A1JSP4 (/IEP) A1JSP4 (/IEP) A1JSP4 (/IEP) A1JSP4 (/IEP) A1JSP4 (/IEP) A1JSP4 (/IEP) A1JSP4 (/IEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
102 P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA) P0AEM6 (/IDA)
(92 more)
Sigma factor antagonist complex GO:1903865
A protein complex which is capable of sigma factor antagonist activity.
1 O67268 (/IDA)
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