The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease III domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: RNA editing complex protein MP90

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 Q384H9 (/IDA) Q384H9 (/IDA)
Nuclease activity GO:0004518
Catalysis of the hydrolysis of ester linkages within nucleic acids.
2 Q4GZ50 (/TAS) Q4GZ50 (/TAS)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
2 Q4GZ50 (/IMP) Q4GZ50 (/IMP)
Ribonuclease III activity GO:0004525
Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
2 Q4GZ50 (/IDA) Q4GZ50 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q4GZ50 (/TAS) Q4GZ50 (/TAS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q4QCV6 (/ISO)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2 Q4GZ50 (/IMP) Q4GZ50 (/IMP)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
2 Q4GZ50 (/TAS) Q4GZ50 (/TAS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q384H9 (/IDA) Q384H9 (/IDA) Q4GZ50 (/IDA) Q4GZ50 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q384H9 (/IDA) Q384H9 (/IDA) Q4GZ50 (/IDA) Q4GZ50 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q384H9 (/RCA) Q384H9 (/RCA) Q4GZ50 (/RCA) Q4GZ50 (/RCA)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
2 Q4GZ50 (/RCA) Q4GZ50 (/RCA)
MRNA editing complex GO:0045293
A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.
2 Q4GZ50 (/IPI) Q4GZ50 (/IPI)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4QCV6 (/ISO)
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