The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cytosolic 5-nucleotidase 3-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
5 B2GUX5 (/IDA) Q9H0P0 (/IDA) Q9H0P0 (/IDA) Q9H0P0 (/IDA) Q9W197 (/IDA)
TRNA 2'-phosphotransferase activity GO:0000215
Catalysis of the reaction: 2'-phospho-
3 Q9H0P0 (/NAS) Q9H0P0 (/NAS) Q9H0P0 (/NAS)
TRNA 2'-phosphotransferase activity GO:0000215
Catalysis of the reaction: 2'-phospho-
3 Q9H0P0 (/TAS) Q9H0P0 (/TAS) Q9H0P0 (/TAS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
3 Q9H0P0 (/NAS) Q9H0P0 (/NAS) Q9H0P0 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q969T7 (/IPI) Q969T7 (/IPI) Q969T7 (/IPI)
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
3 Q5ZID6 (/ISS) Q5ZID6 (/ISS) Q9D020 (/ISS)
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
3 Q9H0P0 (/NAS) Q9H0P0 (/NAS) Q9H0P0 (/NAS)
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
3 Q969T7 (/TAS) Q969T7 (/TAS) Q969T7 (/TAS)
Nucleotidase activity GO:0008252
Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.
1 Q9W197 (/IDA)
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
1 Q9D020 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyrimidine nucleoside metabolic process GO:0006213
The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
3 Q9H0P0 (/NAS) Q9H0P0 (/NAS) Q9H0P0 (/NAS)
Exonucleolytic catabolism of deadenylated mRNA GO:0043928
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.
3 Q969T7 (/TAS) Q969T7 (/TAS) Q969T7 (/TAS)
Pyrimidine nucleoside catabolic process GO:0046135
The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
3 Q9H0P0 (/TAS) Q9H0P0 (/TAS) Q9H0P0 (/TAS)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
3 Q9H0P0 (/IDA) Q9H0P0 (/IDA) Q9H0P0 (/IDA)
Ribonucleoside monophosphate catabolic process GO:0009158
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
1 Q9W197 (/IDA)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
1 Q9W197 (/IDA)
Adenosine metabolic process GO:0046085
The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
1 B2GUX5 (/IDA)
Adenosine metabolic process GO:0046085
The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
1 Q9D020 (/ISO)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
1 Q9D020 (/ISO)
Guanosine-containing compound catabolic process GO:1901069
The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).
1 Q9W197 (/IDA)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q969T7 (/TAS) Q969T7 (/TAS) Q969T7 (/TAS) Q9H0P0 (/TAS) Q9H0P0 (/TAS) Q9H0P0 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q9H0P0 (/IDA) Q9H0P0 (/IDA) Q9H0P0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q5ZID6 (/ISS) Q5ZID6 (/ISS) Q9D020 (/ISS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
3 Q9H0P0 (/IDA) Q9H0P0 (/IDA) Q9H0P0 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
3 Q5ZID6 (/ISS) Q5ZID6 (/ISS) Q9D020 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 F4ITW1 (/IDA) Q9W197 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9D020 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9D020 (/HDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9D020 (/ISO)
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