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CATH Superfamily 1.10.150.290

S-adenosyl-L-methionine-dependent methyltransferases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
S-adenosyl-L-methionine-dependent methyltransferases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Trans-aconitate 2-methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Trans-aconitate 2-methyltransferase. [EC: 2.1.1.144]
S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.
  • Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly.
  • While the enzyme from Escherichia coli forms (E)-3-(methoxycarbonyl)- pent-2-enedioate as the product, that from Saccharomyces cerevisiae forms (E)-2-(methoxycarbonylmethyl)butenedioate and is therefore classified as a separate enzyme (cf. EC 2.1.1.145).
 144 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4 A0A045IRL4
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