The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Flavinator of succinate dehydrogenase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Succinate dehydrogenase assembly factor 2, mitocho...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q08230 (/IPI) Q08230 (/IPI) Q08230 (/IPI) Q08230 (/IPI) Q9NX18 (/IPI)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q4V5I9 (/ISM) Q4V5I9 (/ISM)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
56 A1Z897 (/ISS) A1Z897 (/ISS) A3GHR8 (/ISS) A3KP74 (/ISS) A5DJ67 (/ISS) A5DT64 (/ISS) A6ZND9 (/ISS) A6ZND9 (/ISS) B0XK69 (/ISS) B1P1W2 (/ISS)
(46 more)
Protein-FAD linkage GO:0018293
The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).
56 A1Z897 (/ISS) A1Z897 (/ISS) A3GHR8 (/ISS) A3KP74 (/ISS) A5DJ67 (/ISS) A5DT64 (/ISS) A6ZND9 (/ISS) A6ZND9 (/ISS) B0XK69 (/ISS) B1P1W2 (/ISS)
(46 more)
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
5 Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP) Q9NX18 (/IMP)
Protein-FAD linkage GO:0018293
The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).
5 Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP) Q9NX18 (/IMP)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
4 Q08230 (/IPI) Q08230 (/IPI) Q08230 (/IPI) Q08230 (/IPI)
Protein flavinylation GO:0017013
The addition of a flavin group to a protein amino acid.
4 Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP)
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
4 Q08230 (/HMP) Q08230 (/HMP) Q08230 (/HMP) Q08230 (/HMP)
Mitochondrial respiratory chain complex II assembly GO:0034553
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.
4 Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP) Q08230 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 Q08230 (/HMP) Q08230 (/HMP) Q08230 (/HMP) Q08230 (/HMP)
Negative regulation of epithelial to mesenchymal transition GO:0010719
Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
2 Q8C6I2 (/IMP) Q9NX18 (/IMP)
Copper ion homeostasis GO:0055070
Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
2 Q4V5I9 (/IEP) Q4V5I9 (/IEP)
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
1 Q8C6I2 (/ISO)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 Q9NX18 (/IGI)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 Q8C6I2 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 Q8C6I2 (/ISO)
Negative regulation of epithelial to mesenchymal transition GO:0010719
Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 Q8C6I2 (/ISO)
Protein-FAD linkage GO:0018293
The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).
1 Q8C6I2 (/ISO)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q9NX18 (/IGI)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q8C6I2 (/IMP)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q8C6I2 (/ISO)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
37 A1Z897 (/ISS) A1Z897 (/ISS) A3KP74 (/ISS) B0XK69 (/ISS) B1P1W2 (/ISS) B3MGU5 (/ISS) B3MI37 (/ISS) B3N6D9 (/ISS) B3N8S9 (/ISS) B4GDB3 (/ISS)
(27 more)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
19 A3GHR8 (/ISS) A5DJ67 (/ISS) A5DT64 (/ISS) A6ZND9 (/ISS) A6ZND9 (/ISS) B3LIY9 (/ISS) B3LIY9 (/ISS) B6HRA4 (/ISS) B8NT06 (/ISS) B9W8P6 (/ISS)
(9 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 Q08230 (/HDA) Q08230 (/HDA) Q08230 (/HDA) Q08230 (/HDA) Q8C6I2 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
4 Q08230 (/IDA) Q08230 (/IDA) Q08230 (/IDA) Q08230 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q584Q5 (/IDA) Q584Q5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q584Q5 (/RCA) Q584Q5 (/RCA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
2 Q584Q5 (/IDA) Q584Q5 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
2 Q584Q5 (/IDA) Q584Q5 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9NX18 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q8C6I2 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q7J6 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9NX18 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8C6I2 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9NX18 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8C6I2 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q4Q7J6 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4Q7J6 (/ISO)
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