The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
5' to 3' exonuclease, C-terminal subdomain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 82: DNA-directed RNA polymerase, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial single subunit type RNA polymerase activity GO:0001065
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
4 Q385J0 (/IMP) Q385J0 (/IMP) Q385J0 (/IMP) Q95WT2 (/IMP)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
4 Q385J0 (/ISM) Q385J0 (/ISM) Q385J0 (/ISM) Q95WT2 (/ISM)
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
4 Q385J0 (/ISM) Q385J0 (/ISM) Q385J0 (/ISM) Q95WT2 (/ISM)
Mitochondrial single subunit type RNA polymerase activity GO:0001065
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1 Q4QAL7 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial DNA replication GO:0006264
The process in which new strands of DNA are synthesized in the mitochondrion.
4 Q385J0 (/IMP) Q385J0 (/IMP) Q385J0 (/IMP) Q95WT2 (/IMP)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
4 Q385J0 (/ISM) Q385J0 (/ISM) Q385J0 (/ISM) Q95WT2 (/ISM)
Mitochondrial transcription GO:0006390
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
4 Q385J0 (/IMP) Q385J0 (/IMP) Q385J0 (/IMP) Q95WT2 (/IMP)
Mitochondrial DNA replication GO:0006264
The process in which new strands of DNA are synthesized in the mitochondrion.
1 Q4QAL7 (/ISO)
Mitochondrial transcription GO:0006390
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
1 Q4QAL7 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q385J0 (/IDA) Q385J0 (/IDA) Q385J0 (/IDA) Q95WT2 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q385J0 (/RCA) Q385J0 (/RCA) Q385J0 (/RCA) Q95WT2 (/RCA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
4 Q385J0 (/IDA) Q385J0 (/IDA) Q385J0 (/IDA) Q95WT2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4QAL7 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4QAL7 (/ISO)