The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"5' to 3' exonuclease, C-terminal subdomain
".
FunFam 56: Meiotic recombination protein DMC1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Recombinase activity GO:0000150
Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
|
17 |
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P50265 (/ISS)
Q0MR21 (/ISS)
Q0MR21 (/ISS)
(7 more) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
17 |
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P50265 (/ISS)
Q0MR21 (/ISS)
Q0MR21 (/ISS)
(7 more) |
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
17 |
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P50265 (/ISS)
Q0MR21 (/ISS)
Q0MR21 (/ISS)
(7 more) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
17 |
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P50265 (/ISS)
Q0MR21 (/ISS)
Q0MR21 (/ISS)
(7 more) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
17 |
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P25453 (/ISS)
P50265 (/ISS)
Q0MR21 (/ISS)
Q0MR21 (/ISS)
(7 more) |
|
Recombinase activity GO:0000150
Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
|
7 | P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
7 | P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) |
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
7 | P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P25453 (/IPI) P25453 (/IPI) P25453 (/IPI) P25453 (/IPI) P25453 (/IPI) P25453 (/IPI) P25453 (/IPI) |
|
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
|
7 | P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
1 | A0A1D8PFE4 (/IGI) |
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
1 | A0A1D8PFE4 (/IGI) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Meiotic joint molecule formation GO:0000709
The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.
|
7 | P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) |
|
Synaptonemal complex assembly GO:0007130
The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
|
7 | P25453 (/IGI) P25453 (/IGI) P25453 (/IGI) P25453 (/IGI) P25453 (/IGI) P25453 (/IGI) P25453 (/IGI) |
|
Reciprocal meiotic recombination GO:0007131
The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
|
7 | P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) |
|
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
7 | P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) P25453 (/IMP) |
|
Meiotic joint molecule formation GO:0000709
The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.
|
1 | A0A1D8PFE4 (/IGI) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Condensed nuclear chromosome GO:0000794
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
|
7 | P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | P25453 (/HDA) P25453 (/HDA) P25453 (/HDA) P25453 (/HDA) P25453 (/HDA) P25453 (/HDA) P25453 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) P25453 (/IDA) |
|
Condensed nuclear chromosome GO:0000794
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
|
1 | A0A1D8PFE4 (/IGI) |