The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: DNA mismatch repair protein MutS

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI)
(9 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
Mismatched DNA binding GO:0030983
Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
Adenine/cytosine mispair binding GO:0032136
Interacting selectively and non-covalently with double-stranded DNA containing an A/C mispair.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
19 P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI) P23909 (/IPI)
(9 more)
ADP binding GO:0043531
Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of DNA recombination GO:0000018
Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
19 P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP)
(9 more)
Mismatch repair GO:0006298
A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
Mismatch repair GO:0006298
A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
19 P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP) P23909 (/IMP)
(9 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
19 P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP) P23909 (/IEP)
(9 more)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
19 P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA) P23909 (/IDA)
(9 more)
Mismatch repair complex GO:0032300
Any complex formed of proteins that act in mismatch repair.
19 P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI) P23909 (/IGI)
(9 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q38F29 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q38F29 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q552L1 (/ISS)
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