The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"DNA-directed RNA polymerase, N-terminal domain
".
FunFam 5: DNA-directed RNA polymerase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA primase activity GO:0003896
Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.
|
3 | P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
|
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
|
3 | P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
|
Mitochondrial promoter sequence-specific DNA binding GO:0001018
Interacting selectively and non-covalently with a DNA region that controls the transcription of the mitochondrial DNA.
|
1 | O13993 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial transcription GO:0006390
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
|
4 | O13993 (/IMP) P13433 (/IMP) P13433 (/IMP) P13433 (/IMP) |
|
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
|
3 | P13433 (/IMP) P13433 (/IMP) P13433 (/IMP) |
|
DNA replication, synthesis of RNA primer GO:0006269
The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.
|
3 | P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
|
Mitochondrial transcription GO:0006390
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
|
3 | P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | O13993 (/HDA) P13433 (/HDA) P13433 (/HDA) P13433 (/HDA) |
|
Mitochondrial DNA-directed RNA polymerase complex GO:0034245
A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.
|
4 | O13993 (/IDA) P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | P13433 (/HDA) P13433 (/HDA) P13433 (/HDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
3 | P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
|
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
|
3 | P13433 (/IDA) P13433 (/IDA) P13433 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O13993 (/IDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | O13993 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O13993 (/HDA) |
