CATH Superfamily 1.10.132.70
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Telomerase reverse transcriptase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Telomerase activity GO:0003720
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Telomerase RNA reverse transcriptase activity GO:0003721
Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template.
|
2 | Q1PS67 (/IDA) Q4KTA7 (/IDA) |
|
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
|
2 | Q1PS67 (/IPI) Q4KTA7 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Telomere maintenance via telomerase GO:0007004
The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
5 | A2THE9 (/IGI) B3DIZ2 (/IGI) B4XPB6 (/IGI) B6ZLJ8 (/IGI) F1QE52 (/IGI) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Age-dependent general metabolic decline GO:0007571
A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Erythrocyte maturation GO:0043249
A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Intestinal epithelial structure maintenance GO:0060729
A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
|
5 | A2THE9 (/IGI) B3DIZ2 (/IGI) B4XPB6 (/IGI) B6ZLJ8 (/IGI) F1QE52 (/IGI) |
|
Intestinal epithelial structure maintenance GO:0060729
A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
|
5 | A2THE9 (/IMP) B3DIZ2 (/IMP) B4XPB6 (/IMP) B6ZLJ8 (/IMP) F1QE52 (/IMP) |
|
Telomere maintenance via telomerase GO:0007004
The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
|
2 | Q1PS67 (/ISS) Q4KTA7 (/ISS) |
|
DNA strand elongation GO:0022616
The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
|
2 | Q1PS67 (/IDA) Q4KTA7 (/IDA) |
|
Anterior/posterior axis specification GO:0009948
The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | Q9DE32 (/IGI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | A2THE9 (/IDA) B3DIZ2 (/IDA) B4XPB6 (/IDA) B6ZLJ8 (/IDA) F1QE52 (/IDA) |
|
Telomerase catalytic core complex GO:0000333
The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.
|
2 | Q1PS67 (/IDA) Q4KTA7 (/IDA) |