The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Phosphodiesterase 10A

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3',5'-cyclic-nucleotide phosphodiesterase. [EC: 3.1.4.17]
Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.
  • Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP.
11 A0A1B1UZR0 A0A1B1UZR0 A0A1B1UZR0 G3QMU8 G3QMU8 G3QMU8 Q8CA95 Q9QYJ6 Q9Y233 Q9Y233
(1 more...)
3',5'-cyclic-GMP phosphodiesterase. [EC: 3.1.4.35]
Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.
    11 A0A1B1UZR0 A0A1B1UZR0 A0A1B1UZR0 G3QMU8 G3QMU8 G3QMU8 Q8CA95 Q9QYJ6 Q9Y233 Q9Y233
    (1 more...)
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