The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 13: Phosphodiesterase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3',5'-cyclic-AMP phosphodiesterase activity GO:0004115
Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate.
1 B7YZV4 (/IDA)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
1 B7YZV4 (/ISM)
3',5'-cyclic-GMP phosphodiesterase activity GO:0047555
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.
1 B7YZV4 (/IDA)
Calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity GO:0048101
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive.
1 B7YZV4 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Multicellular organism reproduction GO:0032504
The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
1 B7YZV4 (/HEP)
CAMP metabolic process GO:0046058
The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
1 B7YZV4 (/IDA)
CGMP metabolic process GO:0046068
The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.
1 B7YZV4 (/IDA)
Male mating behavior GO:0060179
The specific behavior of a male organism that is associated with reproduction.
1 B7YZV4 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 B7YZV4 (/HDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...