CATH Superfamily 1.10.1300.10
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
".
FunFam 12: Phosphodiesterase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
3',5'-cyclic-AMP phosphodiesterase activity GO:0004115
Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate.
|
2 | Q01064 (/IDA) Q01064 (/IDA) |
Calmodulin-dependent cyclic-nucleotide phosphodiesterase activity GO:0004117
Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.
|
2 | Q01064 (/TAS) Q01064 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q01064 (/IPI) Q01064 (/IPI) |
3',5'-cyclic-GMP phosphodiesterase activity GO:0047555
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.
|
2 | Q01064 (/IDA) Q01064 (/IDA) |
Cyclic-nucleotide phosphodiesterase activity GO:0004112
Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
|
1 | Q01066 (/IDA) |
Cyclic-nucleotide phosphodiesterase activity GO:0004112
Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
|
1 | Q01065 (/ISO) |
3',5'-cyclic-AMP phosphodiesterase activity GO:0004115
Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate.
|
1 | Q01065 (/ISO) |
Calmodulin-dependent cyclic-nucleotide phosphodiesterase activity GO:0004117
Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.
|
1 | Q01061 (/IDA) |
Calmodulin-dependent cyclic-nucleotide phosphodiesterase activity GO:0004117
Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.
|
1 | Q01065 (/ISO) |
3',5'-cyclic-GMP phosphodiesterase activity GO:0047555
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.
|
1 | Q01065 (/ISO) |
Calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity GO:0048101
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive.
|
1 | Q01061 (/IDA) |
Calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity GO:0048101
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive.
|
1 | Q01065 (/ISO) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | Q01064 (/TAS) Q01064 (/TAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
2 | Q01064 (/TAS) Q01064 (/TAS) |
Monocyte differentiation GO:0030224
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
|
2 | Q01064 (/IEP) Q01064 (/IEP) |
Cellular response to macrophage colony-stimulating factor stimulus GO:0036006
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
|
2 | Q01064 (/IDA) Q01064 (/IDA) |
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
|
2 | Q01064 (/IDA) Q01064 (/IDA) |
Regulation of neurotransmitter levels GO:0001505
Any process that modulates levels of neurotransmitter.
|
1 | Q01065 (/IMP) |
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
|
1 | Q01065 (/IGI) |
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
|
1 | Q01065 (/IMP) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | Q01065 (/IMP) |
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | Q01065 (/IMP) |
Visual learning GO:0008542
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
|
1 | Q01065 (/IGI) |
Visual learning GO:0008542
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
|
1 | Q01065 (/IMP) |
Cellular response to macrophage colony-stimulating factor stimulus GO:0036006
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
|
1 | Q01065 (/ISO) |
Regulation of dopamine metabolic process GO:0042053
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
|
1 | Q01065 (/IMP) |
Serotonin metabolic process GO:0042428
The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
|
1 | Q01065 (/IMP) |
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
|
1 | Q01065 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q01064 (/TAS) Q01064 (/TAS) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q01066 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q01065 (/ISO) |