The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-/4-kinase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: Serine/threonine-protein kinase TOR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9FR53 (/IPI) Q9FR53 (/IPI)
1-phosphatidylinositol-3-kinase activity GO:0016303
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
2 Q9FR53 (/ISS) Q9FR53 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q9FR53 (/IPI) Q9FR53 (/IPI)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
2 Q9FR53 (/IPI) Q9FR53 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA transcription GO:0009303
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Gravitropism GO:0009630
The orientation of plant parts under the stimulation of gravity.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Sucrose mediated signaling GO:0009745
A series of molecular signals mediated by the detection of sucrose.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of abscisic acid biosynthetic process GO:0010116
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of auxin mediated signaling pathway GO:0010929
Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of brassinosteroid mediated signaling pathway GO:1900459
Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Response to rapamycin GO:1901355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Positive regulation of glucose mediated signaling pathway GO:1902661
Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
2 Q9FR53 (/IMP) Q9FR53 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
2 Q9FR53 (/IDA) Q9FR53 (/IDA)
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