CATH Superfamily 1.10.1040.10
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".
FunFam 3: Ketol-acid reductoisomerase, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
6 | P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) |
|
Ketol-acid reductoisomerase activity GO:0004455
Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
|
6 | P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) |
|
Ketol-acid reductoisomerase activity GO:0004455
Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
|
2 | Q5BAA4 (/ISA) Q5BAA4 (/ISA) |
|
Ketol-acid reductoisomerase activity GO:0004455
Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
|
2 | Q5BAA4 (/RCA) Q5BAA4 (/RCA) |
|
Ketol-acid reductoisomerase activity GO:0004455
Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
|
1 | P78827 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
|
6 | P06168 (/IGI) P06168 (/IGI) P06168 (/IGI) P06168 (/IGI) P06168 (/IGI) P06168 (/IGI) |
|
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
|
6 | P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) |
|
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
6 | P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) P06168 (/IMP) |
|
Branched-chain amino acid metabolic process GO:0009081
The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
2 | Q5BAA4 (/RCA) Q5BAA4 (/RCA) |
|
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
2 | Q5BAA4 (/ISA) Q5BAA4 (/ISA) |
|
Coenzyme biosynthetic process GO:0009108
The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
|
2 | Q5BAA4 (/RCA) Q5BAA4 (/RCA) |
|
Leucine metabolic process GO:0006551
The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
|
1 | P78827 (/ISS) |
|
Isoleucine biosynthetic process GO:0009097
The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
|
1 | P78827 (/ISS) |
|
Valine biosynthetic process GO:0009099
The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
|
1 | P78827 (/ISS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
7 | P06168 (/HDA) P06168 (/HDA) P06168 (/HDA) P06168 (/HDA) P06168 (/HDA) P06168 (/HDA) P78827 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) |
|
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
|
6 | P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) P06168 (/IDA) |