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CATH Superfamily 1.10.1040.10

N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Glyoxylate/succinic semialdehyde reductase 2

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinic semialdehyde reductase. [EC: 1.1.1.n11]
4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH.
    		 8 A0A178VK60 A0A178VK60 A0A178WM95 A0A178WM95 F4I907 F4I907 Q9LSV0 Q9LSV0
    Glyoxylate reductase (NADP(+)). [EC: 1.1.1.79]
    Glycolate + NADP(+) = glyoxylate + NADPH.
    • Also reduces hydroxypyruvate to glycerate.
    • Has some affinity for NAD(+).
    		 8 A0A178VK60 A0A178VK60 A0A178WM95 A0A178WM95 F4I907 F4I907 Q9LSV0 Q9LSV0