The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: 2-dehydropantoate 2-reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
2-dehydropantoate 2-reductase activity GO:0008677
Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH.
55 P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA)
(45 more)
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
55 P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA) P0A9J4 (/IDA)
(45 more)
2-dehydropantoate 2-reductase activity GO:0008677
Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH.
7 Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pantothenate biosynthetic process from valine GO:0033317
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid, from other compounds, including valine.
55 P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP) P0A9J4 (/IMP)
(45 more)
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
7 Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS) Q9KPQ9 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.