The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Arf Nucleotide-binding Site Opener,domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: IQ motif and SEC7 domain-containing protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ARF guanyl-nucleotide exchange factor activity GO:0005086
Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
7 E1JI59 (/ISS) Q5U112 (/ISS) Q5U159 (/ISS) Q6U9V3 (/ISS) Q7KTX2 (/ISS) Q95U36 (/ISS) Q9VP80 (/ISS)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
7 E1JI59 (/IDA) Q5U112 (/IDA) Q5U159 (/IDA) Q6U9V3 (/IDA) Q7KTX2 (/IDA) Q95U36 (/IDA) Q9VP80 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
7 E1JI59 (/IMP) Q5U112 (/IMP) Q5U159 (/IMP) Q6U9V3 (/IMP) Q7KTX2 (/IMP) Q95U36 (/IMP) Q9VP80 (/IMP)
Myoblast fusion GO:0007520
A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
7 E1JI59 (/IMP) Q5U112 (/IMP) Q5U159 (/IMP) Q6U9V3 (/IMP) Q7KTX2 (/IMP) Q95U36 (/IMP) Q9VP80 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
7 E1JI59 (/IMP) Q5U112 (/IMP) Q5U159 (/IMP) Q6U9V3 (/IMP) Q7KTX2 (/IMP) Q95U36 (/IMP) Q9VP80 (/IMP)
Positive regulation of ARF protein signal transduction GO:0032014
Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.
7 E1JI59 (/ISS) Q5U112 (/ISS) Q5U159 (/ISS) Q6U9V3 (/ISS) Q7KTX2 (/ISS) Q95U36 (/ISS) Q9VP80 (/ISS)
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
1 Q7KTX2 (/IGI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
7 E1JI59 (/ISS) Q5U112 (/ISS) Q5U159 (/ISS) Q6U9V3 (/ISS) Q7KTX2 (/ISS) Q95U36 (/ISS) Q9VP80 (/ISS)
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