The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 866: Dharma

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Determination of left/right asymmetry in lateral mesoderm GO:0003140
The establishment of the lateral mesoderm with respect to the left and right halves.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Embryonic heart tube morphogenesis GO:0003143
The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Notochord formation GO:0014028
The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Notochord development GO:0030903
The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Floor plate development GO:0033504
The progression of the floor plate over time from its initial formation until its mature state.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743
Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
3 B2GRU4 (/IGI) F1R8X3 (/IGI) O93236 (/IGI)
Developmental pigmentation GO:0048066
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Axial mesoderm morphogenesis GO:0048319
The process in which the anatomical structures of the axial mesoderm are generated and organized.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Axial mesoderm formation GO:0048320
The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Eye morphogenesis GO:0048592
The process in which the anatomical structures of the eye are generated and organized.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Spemann organizer formation GO:0060061
Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Somite development GO:0061053
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)
Regulation of BMP signaling pathway involved in heart jogging GO:2000223
Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging.
3 B2GRU4 (/IMP) F1R8X3 (/IMP) O93236 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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