The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 41: insulin gene enhancer protein ISL-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 35 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
169 G5EC36 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI)
(159 more)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
162 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(152 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
108 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(98 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
58 P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA)
(48 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
58 P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA) P61371 (/ISA)
(48 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
58 P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM) P61371 (/ISM)
(48 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
58 P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS)
(48 more)
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
58 P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI)
(48 more)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
54 P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA)
(44 more)
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
54 P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS)
(44 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Nuclear receptor binding GO:0016922
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
Nuclear receptor binding GO:0016922
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
54 P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI) P61374 (/IPI)
(44 more)
Nuclear receptor binding GO:0016922
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Nuclear receptor binding GO:0016922
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Estrogen receptor binding GO:0030331
Interacting selectively and non-covalently with an estrogen receptor.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
BHLH transcription factor binding GO:0043425
Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
54 P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI) P61371 (/IPI)
(44 more)
BHLH transcription factor binding GO:0043425
Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
54 P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS)
(44 more)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
4 P92031 (/IDA) Q9VJ37 (/IDA) Q9VJ37 (/IDA) Q9Y0Z9 (/IDA)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
4 P92031 (/IDA) Q9VJ37 (/IDA) Q9VJ37 (/IDA) Q9Y0Z9 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
4 Q96A47 (/ISS) Q96A47 (/ISS) Q96A47 (/ISS) Q96A47 (/ISS)

There are 156 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
164 P50211 (/ISS) P53405 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(154 more)
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
162 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(152 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
112 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(102 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
110 P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI) P61371 (/IGI)
(100 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
110 P50211 (/ISS) P53405 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(100 more)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
58 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(48 more)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
58 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(48 more)
Neuron fate specification GO:0048665
The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
57 P53405 (/IMP) P53406 (/IMP) P53406 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(47 more)
Spinal cord motor neuron cell fate specification GO:0021520
The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
56 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(46 more)
Visceral motor neuron differentiation GO:0021524
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
56 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(46 more)
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
56 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(46 more)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
56 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(46 more)
Neuron fate commitment GO:0048663
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
56 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(46 more)
Secondary heart field specification GO:0003139
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
55 P53407 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP) P61371 (/IMP)
(45 more)
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
55 P53405 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(45 more)
Peripheral nervous system neuron axonogenesis GO:0048936
Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
55 P53405 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(45 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Neural crest cell migration GO:0001755
The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Secondary heart field specification GO:0003139
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Endocardial cushion morphogenesis GO:0003203
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Endocardial cushion morphogenesis GO:0003203
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Regulation of secondary heart field cardioblast proliferation GO:0003266
Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of vascular endothelial growth factor production GO:0010575
Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of vascular endothelial growth factor production GO:0010575
Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
54 P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP)
(44 more)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Trigeminal nerve development GO:0021559
The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Trigeminal nerve development GO:0021559
The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Pituitary gland development GO:0021983
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Axon regeneration GO:0031103
The regrowth of axons following their loss or damage.
54 P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP)
(44 more)
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
54 P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC) P61371 (/IC)
(44 more)
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
54 P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP)
(44 more)
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725
Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725
Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of interleukin-1 alpha production GO:0032730
Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of interleukin-1 alpha production GO:0032730
Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of interleukin-1 beta production GO:0032731
Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of interleukin-1 beta production GO:0032731
Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of interleukin-12 production GO:0032735
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of interleukin-12 production GO:0032735
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of interleukin-6 production GO:0032755
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of interleukin-6 production GO:0032755
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Negative regulation of intracellular estrogen receptor signaling pathway GO:0033147
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
Negative regulation of intracellular estrogen receptor signaling pathway GO:0033147
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Negative regulation of intracellular estrogen receptor signaling pathway GO:0033147
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of histone acetylation GO:0035066
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Positive regulation of tyrosine phosphorylation of STAT protein GO:0042531
Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
54 P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS) P61372 (/ISS)
(44 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Neuron fate specification GO:0048665
The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Mesenchymal cell differentiation GO:0048762
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Mesenchymal cell differentiation GO:0048762
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Sensory system development GO:0048880
The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Sensory system development GO:0048880
The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Peripheral nervous system neuron development GO:0048935
The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Peripheral nervous system neuron axonogenesis GO:0048936
Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
54 P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP) P61374 (/IMP)
(44 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Ventricular cardiac muscle tissue morphogenesis GO:0055010
The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Ventricular cardiac muscle tissue morphogenesis GO:0055010
The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Pharyngeal system development GO:0060037
The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Pharyngeal system development GO:0060037
The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Cardiac muscle cell myoblast differentiation GO:0060379
The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Innervation GO:0060384
The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Innervation GO:0060384
The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Atrial septum morphogenesis GO:0060413
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Atrial septum morphogenesis GO:0060413
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Cardiac cell fate determination GO:0060913
The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
54 P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA)
(44 more)
Cardiac cell fate determination GO:0060913
The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
54 P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP) P61372 (/IMP)
(44 more)
Cardiac cell fate determination GO:0060913
The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Cellular response to glucocorticoid stimulus GO:0071385
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
54 P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP) P61374 (/IEP)
(44 more)
Cellular response to glucocorticoid stimulus GO:0071385
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Positive regulation of granulocyte colony-stimulating factor production GO:0071657
Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of granulocyte colony-stimulating factor production GO:0071657
Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Negative regulation of protein homodimerization activity GO:0090074
Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
54 P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA) P61374 (/IDA)
(44 more)
Negative regulation of protein homodimerization activity GO:0090074
Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Negative regulation of protein homodimerization activity GO:0090074
Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
54 P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI) P61372 (/IGI)
(44 more)
Positive regulation of macrophage colony-stimulating factor production GO:1901258
Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.
54 P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(44 more)
Positive regulation of macrophage colony-stimulating factor production GO:1901258
Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.
54 P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS) P61371 (/ISS)
(44 more)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
6 P53406 (/IMP) P53406 (/IMP) P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Germ-band shortening GO:0007390
The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Muscle cell fate determination GO:0007521
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
4 P92031 (/NAS) Q9VJ37 (/NAS) Q9VJ37 (/NAS) Q9Y0Z9 (/NAS)
Chaeta morphogenesis GO:0008407
The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
4 P53405 (/IGI) P53406 (/IGI) P53406 (/IGI) P53407 (/IGI)
Notum cell fate specification GO:0035310
The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
4 P92031 (/IDA) Q9VJ37 (/IDA) Q9VJ37 (/IDA) Q9Y0Z9 (/IDA)
Amnioserosa maintenance GO:0046665
Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Lymph gland development GO:0048542
The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
4 Q96A47 (/TAS) Q96A47 (/TAS) Q96A47 (/TAS) Q96A47 (/TAS)
Peripheral nervous system neuron development GO:0048935
The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
4 Q96A47 (/TAS) Q96A47 (/TAS) Q96A47 (/TAS) Q96A47 (/TAS)
Dendrite guidance GO:0070983
The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.
4 P92031 (/IMP) Q9VJ37 (/IMP) Q9VJ37 (/IMP) Q9Y0Z9 (/IMP)
Neuron fate specification GO:0048665
The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
3 P53405 (/IGI) P53406 (/IGI) P53406 (/IGI)
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
3 P53405 (/IMP) P53406 (/IMP) P53406 (/IMP)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
2 P53406 (/IGI) P53406 (/IGI)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
2 P53406 (/IMP) P53406 (/IMP)
Visceral motor neuron differentiation GO:0021524
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2 Q9CXV0 (/IMP) Q9CXV0 (/IMP)
Embryonic heart tube development GO:0035050
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
2 Q9VJ37 (/IMP) Q9VJ37 (/IMP)
Angioblast cell migration GO:0035476
The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.
2 P53406 (/IMP) P53406 (/IMP)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
2 Q9CXV0 (/IMP) Q9CXV0 (/IMP)
Neuron fate commitment GO:0048663
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
2 Q9CXV0 (/IMP) Q9CXV0 (/IMP)
Venous blood vessel morphogenesis GO:0048845
The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.
2 P53406 (/IMP) P53406 (/IMP)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
1 G5EC36 (/IMP)
Pancreatic A cell development GO:0003322
The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
1 P53405 (/IMP)
Type B pancreatic cell development GO:0003323
The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
1 P53405 (/IMP)
Pancreatic D cell development GO:0003324
The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.
1 P53405 (/IMP)
Excretion GO:0007588
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
1 G5EC36 (/IMP)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
1 P53405 (/IMP)
Body morphogenesis GO:0010171
The process in which the anatomical structures of the soma are generated and organized.
1 G5EC36 (/IMP)
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
1 P53405 (/IGI)
Spinal cord association neuron differentiation GO:0021527
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
1 P53405 (/IMP)
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
1 P53405 (/IMP)
Endocrine pancreas development GO:0031018
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
1 P53405 (/IMP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
1 P53410 (/IDA)
Gonad morphogenesis GO:0035262
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
1 G5EC36 (/IMP)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
1 G5EC36 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P50211 (/IDA)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 P53405 (/IMP)
Atrial cardiac muscle cell differentiation GO:0055011
The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
1 P53405 (/IMP)
Head morphogenesis GO:0060323
The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
1 G5EC36 (/IMP)
Pharynx development GO:0060465
The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.
1 G5EC36 (/IMP)
GABAergic neuron differentiation GO:0097154
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
1 P53405 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
117 G5EC36 (/IDA) P50211 (/IDA) P53405 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA) P61372 (/IDA)
(107 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
59 D6RBJ1 (/IDA) D6RBJ1 (/IDA) D6RBJ1 (/IDA) D6RBJ1 (/IDA) D6RBJ1 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA) P61371 (/IDA)
(49 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
54 P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS) P61373 (/ISS)
(44 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
54 P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS)
(44 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
54 P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO) P61372 (/ISO)
(44 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
54 P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS) P61372 (/TAS)
(44 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
54 P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS) P61371 (/NAS)
(44 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q96A47 (/IC) Q96A47 (/IC) Q96A47 (/IC) Q96A47 (/IC)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 P50211 (/IDA) P53410 (/IDA)
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