The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 321: Small nuclear RNA-activating complex, polypeptide ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q5SXM2 (/ISA) Q5SXM2 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q5SXM2 (/ISM) Q5SXM2 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q5SXM2 (/NAS) Q5SXM2 (/NAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 Q5SXM2 (/IDA) Q5SXM2 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 Q9LV31 (/ISS) Q9LV31 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 Q8BP86 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 Q8BP86 (/ISS)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
3 F1QVS5 (/IMP) F1R7G5 (/IMP) I1V1W6 (/IMP)
Intrahepatic bile duct development GO:0035622
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
3 F1QVS5 (/IMP) F1R7G5 (/IMP) I1V1W6 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9LV31 (/TAS) Q9LV31 (/TAS)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
SnRNA transcription GO:0009301
The synthesis of small nuclear RNA (snRNA) from a DNA template.
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
2 Q5SXM2 (/IDA) Q5SXM2 (/IDA)
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
SnRNA transcription by RNA polymerase III GO:0042796
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
2 Q5SXM2 (/IDA) Q5SXM2 (/IDA)
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
1 Q8BP86 (/ISO)
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
1 Q8BP86 (/ISS)
SnRNA transcription by RNA polymerase III GO:0042796
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
1 Q8BP86 (/ISO)
SnRNA transcription by RNA polymerase III GO:0042796
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
1 Q8BP86 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q5SXM2 (/IC) Q5SXM2 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q5SXM2 (/TAS) Q5SXM2 (/TAS)
SnRNA-activating protein complex GO:0019185
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
2 Q5SXM2 (/IDA) Q5SXM2 (/IDA)
SnRNA-activating protein complex GO:0019185
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
1 Q8BP86 (/ISO)
SnRNA-activating protein complex GO:0019185
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
1 Q8BP86 (/ISS)
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