The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Iroquois-class homeobox protein IRX

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 21 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
10 P78411 (/ISA) P78412 (/ISA) P78413 (/ISA) P78414 (/ISA) P78414 (/ISA) P78415 (/ISA) Q8IYA7 (/ISA) Q8IYA7 (/ISA) Q8IYA7 (/ISA) Q9BZI1 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
10 P78411 (/ISM) P78412 (/ISM) P78413 (/ISM) P78414 (/ISM) P78414 (/ISM) P78415 (/ISM) Q8IYA7 (/ISM) Q8IYA7 (/ISM) Q8IYA7 (/ISM) Q9BZI1 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
6 P78412 (/NAS) P78413 (/NAS) P78414 (/NAS) P78414 (/NAS) P78415 (/NAS) Q9BZI1 (/NAS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 M9PI45 (/IDA) O01667 (/IDA) Q24248 (/IDA) Q8BIA3 (/IDA) Q9VU01 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
4 M9PI45 (/ISS) O01667 (/ISS) P54269 (/ISS) Q9VU01 (/ISS)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P78414 (/IC) P78414 (/IC) Q9BZI1 (/IC)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 A5YC44 (/IDA) A5YC45 (/IDA) A9UGK1 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 A5YC44 (/IGI) A5YC45 (/IGI) A9UGK1 (/IGI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 M9PI45 (/IPI) O01667 (/IPI) Q9VU01 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 P78414 (/IDA) P78414 (/IDA) Q9BZI1 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q8BIA3 (/IDA) Q9ER75 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 Q8BIA3 (/IDA) Q9ER75 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 P81066 (/ISO) P81068 (/ISO)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q9YGK8 (/IDA) Q9YGK8 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q8BIA3 (/IDA)
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
1 Q8BIA3 (/IPI)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q8BIA3 (/IMP)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q8BIA3 (/IMP)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 P54269 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8BIA3 (/IPI)

There are 146 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
9 M9PI45 (/IDA) O01667 (/IDA) P78414 (/IDA) P78414 (/IDA) Q8BIA3 (/IDA) Q9BZI1 (/IDA) Q9VU01 (/IDA) Q9YGK8 (/IDA) Q9YGK8 (/IDA)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
9 O42261 (/IMP) O42261 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP) Q90XW5 (/IMP) Q90XW6 (/IMP) Q90XW6 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
9 O42261 (/IMP) O42261 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP) Q90XW5 (/IMP) Q90XW6 (/IMP) Q90XW6 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Proximal/distal pattern formation GO:0009954
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
9 O42261 (/IMP) O42261 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP) Q90XW5 (/IMP) Q90XW6 (/IMP) Q90XW6 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Retina morphogenesis in camera-type eye GO:0060042
The process in which the anatomical structure of the retina is generated and organized.
8 A0A0R4ILR3 (/IMP) A0A2R8RSU7 (/IMP) B3DKL9 (/IMP) Q5I8Y1 (/IMP) Q6P0B6 (/IMP) Q7SZP0 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
7 O42261 (/IDA) O42261 (/IDA) Q6DCQ1 (/IDA) Q6DCQ1 (/IDA) Q9ER75 (/IDA) Q9YGK8 (/IDA) Q9YGK8 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
7 M9PI45 (/ISS) O01667 (/ISS) Q2TAQ8 (/ISS) Q66IK1 (/ISS) Q6F2E3 (/ISS) Q6NVN3 (/ISS) Q9VU01 (/ISS)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
6 O42261 (/IMP) O42261 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
6 O42261 (/IMP) O42261 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
6 O42261 (/IDA) O42261 (/IDA) Q6DCQ1 (/IDA) Q6DCQ1 (/IDA) Q9YGK8 (/IDA) Q9YGK8 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
6 Q24248 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP) Q8BIA3 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
6 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q504I0 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP) Q90YX8 (/IMP)
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
5 M9PI45 (/IMP) O01667 (/IMP) P54269 (/IMP) Q24248 (/IMP) Q9VU01 (/IMP)
Gastrulation GO:0007369
A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
5 A0A286Y9M4 (/IMP) A7YYJ6 (/IMP) Q568V7 (/IMP) Q90Z68 (/IMP) Q9PVD8 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
5 Q2TAQ8 (/ISS) Q4LDQ3 (/ISS) Q66IK1 (/ISS) Q6F2E3 (/ISS) Q6NVN3 (/ISS)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
5 Q2TAQ8 (/ISS) Q4LDQ3 (/ISS) Q66IK1 (/ISS) Q6F2E3 (/ISS) Q6NVN3 (/ISS)
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
5 Q504I0 (/IGI) Q6DEL0 (/IGI) Q8JJ47 (/IGI) Q90YN0 (/IGI) Q90YX8 (/IGI)
Endocrine pancreas development GO:0031018
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
5 A0A286Y9M4 (/IMP) A7YYJ6 (/IMP) Q568V7 (/IMP) Q90Z68 (/IMP) Q9PVD8 (/IMP)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
5 M9PI45 (/IMP) O01667 (/IMP) P54269 (/IMP) Q24248 (/IMP) Q9VU01 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
5 P54269 (/ISS) Q2TAQ8 (/ISS) Q66IK1 (/ISS) Q6F2E3 (/ISS) Q6NVN3 (/ISS)
Neural plate development GO:0001840
The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
4 O42261 (/IMP) O42261 (/IMP) Q6DCQ1 (/IMP) Q6DCQ1 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
4 A0A0R4ILR3 (/IDA) B3DKL9 (/IDA) Q8JH33 (/IDA) Q90XQ7 (/IDA)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
4 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
4 M9PI45 (/IMP) O01667 (/IMP) Q24248 (/IMP) Q9VU01 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
4 B7ZRT8 (/ISS) Q688D0 (/ISS) Q90XW6 (/ISS) Q90XW6 (/ISS)
Proximal/distal pattern formation GO:0009954
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
4 Q2TAQ8 (/ISS) Q4LDQ3 (/ISS) Q66IK1 (/ISS) Q6F2E3 (/ISS)
Central nervous system neuron differentiation GO:0021953
The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.
4 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Embryonic camera-type eye development GO:0031076
The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
4 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Regulation of chondrocyte differentiation GO:0032330
Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
4 Q1LXU5 (/IGI) Q504I0 (/IGI) Q90YM9 (/IGI) Q90YX8 (/IGI)
Embryonic pectoral fin morphogenesis GO:0035118
The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
4 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Specification of pronephric tubule identity GO:0039005
The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.
4 O42261 (/IMP) O42261 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Eye photoreceptor cell development GO:0042462
Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.
4 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Inner ear morphogenesis GO:0042472
The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
4 A0A0R4ILR3 (/IMP) B3DKL9 (/IMP) Q8JH33 (/IMP) Q90XQ7 (/IMP)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
4 F1Q7T5 (/IMP) O42261 (/IMP) O42261 (/IMP) Q6NY58 (/IMP)
Maintenance of kidney identity GO:0072005
The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
4 O42261 (/IMP) O42261 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Proximal/distal pattern formation involved in pronephric nephron development GO:0072196
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
4 O42261 (/IMP) O42261 (/IMP) Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Embryonic skeletal joint development GO:0072498
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.
4 Q1LXU5 (/IGI) Q504I0 (/IGI) Q90YM9 (/IGI) Q90YX8 (/IGI)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 O42261 (/IMP) O42261 (/IMP) Q8BIA3 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 Q2TAQ8 (/ISS) Q6F2E3 (/ISS) Q6NVN3 (/ISS)
Metanephros development GO:0001656
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
3 P81066 (/IEP) P81067 (/IEP) P81068 (/IEP)
Metanephros development GO:0001656
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
3 M9PI45 (/IEP) O01667 (/IEP) Q9VU01 (/IEP)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
3 M9PI45 (/IMP) O01667 (/IMP) Q9VU01 (/IMP)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
3 M9PI45 (/IMP) O01667 (/IMP) Q9VU01 (/IMP)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
3 Q8IYA7 (/ISS) Q8IYA7 (/ISS) Q8IYA7 (/ISS)
Retina layer formation GO:0010842
The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
3 Q504I0 (/IMP) Q90YX8 (/IMP) Q9ER75 (/IMP)
Equator specification GO:0045317
The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
3 M9PI45 (/IMP) O01667 (/IMP) Q9VU01 (/IMP)
Myoblast differentiation GO:0045445
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
3 A5YC44 (/IMP) A5YC45 (/IMP) A9UGK1 (/IMP)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
3 Q9ER75 (/IDA) Q9YGK8 (/IDA) Q9YGK8 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
3 A5YC44 (/IMP) A5YC45 (/IMP) A9UGK1 (/IMP)
Dorsal appendage formation GO:0046843
Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
3 M9PI45 (/IMP) O01667 (/IMP) Q9VU01 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
3 A5YC44 (/IMP) A5YC45 (/IMP) A9UGK1 (/IMP)
Proximal/distal pattern formation involved in nephron development GO:0072047
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Specification of loop of Henle identity GO:0072086
The process in which the loop of Henle of the kidney nephron acquires its identity.
3 P81066 (/IEP) P81067 (/IEP) P81068 (/IEP)
Specification of loop of Henle identity GO:0072086
The process in which the loop of Henle of the kidney nephron acquires its identity.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Sensory neuron axon guidance GO:0097374
The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.
3 M9PI45 (/IMP) O01667 (/IMP) Q9VU01 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P81066 (/ISO) P81068 (/ISO)
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
2 O42261 (/IMP) O42261 (/IMP)
Neural plate development GO:0001840
The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
2 Q66IK1 (/ISS) Q6NVN3 (/ISS)
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
2 P54269 (/IGI) Q24248 (/IGI)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
2 P78411 (/IMP) Q90XW5 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 Q8BIA3 (/IMP) Q9JKQ4 (/IMP)
Neural crest cell fate specification GO:0014036
The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Neural crest cell fate specification GO:0014036
The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Hindbrain morphogenesis GO:0021575
The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
2 Q504I0 (/IMP) Q90YX8 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
2 Q504I0 (/IMP) Q90YX8 (/IMP)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Midbrain-hindbrain boundary development GO:0030917
The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Midbrain-hindbrain boundary development GO:0030917
The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Regulation of chondrocyte differentiation GO:0032330
Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
2 Q504I0 (/IMP) Q90YX8 (/IMP)
Pronephric nephron tubule epithelial cell differentiation GO:0035778
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.
2 F1Q7T5 (/IMP) Q6NY58 (/IMP)
Specification of pronephric tubule identity GO:0039005
The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Pronephric duct morphogenesis GO:0039023
The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.
2 F1Q7T5 (/IGI) Q6NY58 (/IGI)
Pronephric duct morphogenesis GO:0039023
The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.
2 F1Q7T5 (/IMP) Q6NY58 (/IMP)
Photoreceptor cell development GO:0042461
Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
2 Q5I8Y0 (/IMP) Q6NZU4 (/IMP)
Muscle cell fate commitment GO:0042693
The process in which the cellular identity of muscle cells is acquired and determined.
2 P54269 (/IGI) Q24248 (/IGI)
Equator specification GO:0045317
The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
2 P54269 (/TAS) Q24248 (/TAS)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
2 Q66IK1 (/ISS) Q6NVN3 (/ISS)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
2 Q66IK1 (/ISS) Q6NVN3 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
2 P78411 (/IMP) Q90XW5 (/IMP)
Posterior lateral line neuromast hair cell differentiation GO:0048923
The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2 Q5I8Y0 (/IMP) Q6NZU4 (/IMP)
Posterior lateral line neuromast mantle cell differentiation GO:0048924
The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2 Q5I8Y0 (/IMP) Q6NZU4 (/IMP)
Embryonic retina morphogenesis in camera-type eye GO:0060059
The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.
2 Q504I0 (/IMP) Q90YX8 (/IMP)
Spemann organizer formation at the dorsal lip of the blastopore GO:0060062
Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.
2 Q9YGK8 (/IMP) Q9YGK8 (/IMP)
Spemann organizer formation at the dorsal lip of the blastopore GO:0060062
Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Maintenance of kidney identity GO:0072005
The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Proximal/distal pattern formation involved in pronephric nephron development GO:0072196
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
2 Q2TAQ8 (/ISS) Q6F2E3 (/ISS)
Proximal/distal pattern formation involved in metanephric nephron development GO:0072272
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
2 P81066 (/IEP) P81068 (/IEP)
Embryonic skeletal joint development GO:0072498
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.
2 Q504I0 (/IMP) Q90YX8 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q9PUR3 (/ISA)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 Q9PUR3 (/ISA)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 P81067 (/ISO)
Neural plate development GO:0001840
The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
1 Q9PUR3 (/ISA)
Regulation of heart rate GO:0002027
Any process that modulates the frequency or rate of heart contraction.
1 Q9JKQ4 (/IMP)
Tendon sheath development GO:0002932
The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.
1 Q8BIA3 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q9QY61 (/ISS)
Regulation of mitotic cell cycle GO:0007346
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
1 P54269 (/IGI)
Regulation of mitotic cell cycle GO:0007346
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
1 P54269 (/IPI)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 Q9PUR3 (/ISA)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
1 P81067 (/IGI)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 Q9QY61 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P78413 (/TAS)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
1 Q8BIA3 (/IEP)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
1 Q4LDQ3 (/ISS)
Detection of visible light GO:0009584
The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
1 Q9ER75 (/IMP)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 Q9PUR3 (/ISA)
Proximal/distal pattern formation GO:0009954
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
1 Q9PUR3 (/ISA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q8BIA3 (/IMP)
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
1 Q8BIA3 (/IMP)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
1 Q8BIA3 (/IMP)
Notum cell fate specification GO:0035310
The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.
1 Q24248 (/IMP)
Tendon cell differentiation GO:0035990
The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
1 Q8BIA3 (/IMP)
Tendon formation GO:0035992
The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.
1 Q8BIA3 (/IMP)
Specification of pronephric tubule identity GO:0039005
The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.
1 Q9PUR3 (/ISA)
Neuron maturation GO:0042551
A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.
1 Q9JKQ4 (/IGI)
Negative regulation of myoblast differentiation GO:0045662
Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
1 Q8BIA3 (/IDA)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
1 P81067 (/IDA)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
1 P81067 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9PUR3 (/ISA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q24248 (/NAS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9PUR3 (/ISA)
Cell development GO:0048468
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
1 Q9JKQ4 (/IMP)
Establishment of animal organ orientation GO:0048561
The process that determines the orientation of an animal organ or tissue with reference to an axis.
1 D3ZRI4 (/IEP)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
1 Q4LDQ3 (/ISS)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
1 Q9PUR3 (/ISA)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
1 Q6NVN3 (/ISS)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
1 Q24248 (/IMP)
Retinal bipolar neuron differentiation GO:0060040
The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.
1 Q9JKQ4 (/IGI)
Retinal bipolar neuron differentiation GO:0060040
The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.
1 Q9ER75 (/IMP)
Maintenance of kidney identity GO:0072005
The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 Q9PUR3 (/ISA)
Proximal/distal pattern formation involved in nephron development GO:0072047
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
1 P81067 (/IEP)
Proximal/distal pattern formation involved in pronephric nephron development GO:0072196
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
1 Q9PUR3 (/ISA)
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
1 P81067 (/IDA)
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
1 P78415 (/ISS)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
18 B7ZRT8 (/ISS) O42261 (/ISS) O42261 (/ISS) P54269 (/ISS) Q24248 (/ISS) Q2TAQ8 (/ISS) Q4LDQ3 (/ISS) Q66IK1 (/ISS) Q688D0 (/ISS) Q6DCQ1 (/ISS)
(8 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 O42261 (/ISS) O42261 (/ISS) Q4LDQ3 (/ISS) Q6NVN3 (/ISS) Q90XW5 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q24248 (/IC) Q9YGK8 (/IC) Q9YGK8 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
3 O42261 (/ISA) O42261 (/ISA) Q9PUR3 (/ISA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P81067 (/IDA) Q93348 (/IDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 Q8BIA3 (/IC)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 Q9QY61 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q24248 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P81067 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P81067 (/IDA)
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