The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 252: Retinal homeobox protein Rx-B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
5 Q24477 (/IDA) Q26441 (/IDA) Q26441 (/IDA) Q7KSE4 (/IDA) Q7KSE4 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 Q24477 (/IDA) Q26441 (/IDA) Q26441 (/IDA) Q7KSE4 (/IDA) Q7KSE4 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
5 Q24477 (/IMP) Q26441 (/IMP) Q26441 (/IMP) Q7KSE4 (/IMP) Q7KSE4 (/IMP)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
5 Q24477 (/IMP) Q26441 (/IMP) Q26441 (/IMP) Q7KSE4 (/IMP) Q7KSE4 (/IMP)
Glial cell differentiation GO:0010001
The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.
5 Q24477 (/NAS) Q26441 (/NAS) Q26441 (/NAS) Q7KSE4 (/NAS) Q7KSE4 (/NAS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
5 Q24477 (/IDA) Q26441 (/IDA) Q26441 (/IDA) Q7KSE4 (/IDA) Q7KSE4 (/IDA)
Glial cell development GO:0021782
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
5 Q24477 (/IMP) Q26441 (/IMP) Q26441 (/IMP) Q7KSE4 (/IMP) Q7KSE4 (/IMP)
Regulation of phagocytosis GO:0050764
Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.
5 Q24477 (/IGI) Q26441 (/IGI) Q26441 (/IGI) Q7KSE4 (/IGI) Q7KSE4 (/IGI)
Regulation of phagocytosis GO:0050764
Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.
5 Q24477 (/IMP) Q26441 (/IMP) Q26441 (/IMP) Q7KSE4 (/IMP) Q7KSE4 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
5 Q24477 (/IMP) Q26441 (/IMP) Q26441 (/IMP) Q7KSE4 (/IMP) Q7KSE4 (/IMP)
Synaptic growth at neuromuscular junction GO:0051124
The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
5 Q24477 (/IMP) Q26441 (/IMP) Q26441 (/IMP) Q7KSE4 (/IMP) Q7KSE4 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q24477 (/IDA) Q26441 (/IDA) Q26441 (/IDA) Q7KSE4 (/IDA) Q7KSE4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q24477 (/IDA) Q26441 (/IDA) Q26441 (/IDA) Q7KSE4 (/IDA) Q7KSE4 (/IDA)
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