The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 169: DNA-binding protein SATB1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
10 O76143 (/ISS) O76143 (/ISS) O77289 (/ISS) O77289 (/ISS) Q8MLT6 (/ISS) Q8MLT6 (/ISS) Q8MQP8 (/ISS) Q8MQP8 (/ISS) Q9W268 (/ISS) Q9W268 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
10 O76143 (/TAS) O76143 (/TAS) O77289 (/TAS) O77289 (/TAS) Q8MLT6 (/TAS) Q8MLT6 (/TAS) Q8MQP8 (/TAS) Q8MQP8 (/TAS) Q9W268 (/TAS) Q9W268 (/TAS)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
1 Q86MI0 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
10 O76143 (/IEP) O76143 (/IEP) O77289 (/IEP) O77289 (/IEP) Q8MLT6 (/IEP) Q8MLT6 (/IEP) Q8MQP8 (/IEP) Q8MQP8 (/IEP) Q9W268 (/IEP) Q9W268 (/IEP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
10 O76143 (/ISS) O76143 (/ISS) O77289 (/ISS) O77289 (/ISS) Q8MLT6 (/ISS) Q8MLT6 (/ISS) Q8MQP8 (/ISS) Q8MQP8 (/ISS) Q9W268 (/ISS) Q9W268 (/ISS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
10 O76143 (/TAS) O76143 (/TAS) O77289 (/TAS) O77289 (/TAS) Q8MLT6 (/TAS) Q8MLT6 (/TAS) Q8MQP8 (/TAS) Q8MQP8 (/TAS) Q9W268 (/TAS) Q9W268 (/TAS)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
10 O76143 (/IMP) O76143 (/IMP) O77289 (/IMP) O77289 (/IMP) Q8MLT6 (/IMP) Q8MLT6 (/IMP) Q8MQP8 (/IMP) Q8MQP8 (/IMP) Q9W268 (/IMP) Q9W268 (/IMP)
Midgut development GO:0007494
The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.
10 O76143 (/IMP) O76143 (/IMP) O77289 (/IMP) O77289 (/IMP) Q8MLT6 (/IMP) Q8MLT6 (/IMP) Q8MQP8 (/IMP) Q8MQP8 (/IMP) Q9W268 (/IMP) Q9W268 (/IMP)
Copper ion import GO:0015677
The directed movement of copper ions into a cell or organelle.
10 O76143 (/IMP) O76143 (/IMP) O77289 (/IMP) O77289 (/IMP) Q8MLT6 (/IMP) Q8MLT6 (/IMP) Q8MQP8 (/IMP) Q8MQP8 (/IMP) Q9W268 (/IMP) Q9W268 (/IMP)
Imaginal disc-derived leg joint morphogenesis GO:0016348
The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.
10 O76143 (/IMP) O76143 (/IMP) O77289 (/IMP) O77289 (/IMP) Q8MLT6 (/IMP) Q8MLT6 (/IMP) Q8MQP8 (/IMP) Q8MQP8 (/IMP) Q9W268 (/IMP) Q9W268 (/IMP)
Reproductive structure development GO:0048608
The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.
10 O76143 (/IMP) O76143 (/IMP) O77289 (/IMP) O77289 (/IMP) Q8MLT6 (/IMP) Q8MLT6 (/IMP) Q8MQP8 (/IMP) Q8MQP8 (/IMP) Q9W268 (/IMP) Q9W268 (/IMP)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 Q86MI0 (/IMP)
Mitochondrial unfolded protein response GO:0034514
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.
1 Q86MI0 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 O76143 (/IDA) O76143 (/IDA) O77289 (/IDA) O77289 (/IDA) Q86MI0 (/IDA) Q8MLT6 (/IDA) Q8MLT6 (/IDA) Q8MQP8 (/IDA) Q8MQP8 (/IDA) Q9W268 (/IDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 O76143 (/IDA) O76143 (/IDA) O77289 (/IDA) O77289 (/IDA) Q8MLT6 (/IDA) Q8MLT6 (/IDA) Q8MQP8 (/IDA) Q8MQP8 (/IDA) Q9W268 (/IDA) Q9W268 (/IDA)
Nuclear transcription factor complex GO:0044798
A protein complex, located in the nucleus, that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 Q86MI0 (/IPI)
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