The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 142: homeobox protein OTX2 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
23 |
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
P32243 (/IPI)
(13 more) |
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
20 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(10 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
20 |
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
P32243 (/ISA)
(10 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
20 |
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
P32243 (/ISM)
(10 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
20 |
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
P32243 (/NAS)
(10 more) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
20 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(10 more) |
Eukaryotic initiation factor 4E binding GO:0008190
Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
|
20 |
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
(10 more) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | F1R982 (/IPI) Q6NYT9 (/IPI) Q8UUZ5 (/IPI) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | Q91813 (/IDA) Q91813 (/IDA) |
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
1 | P80206 (/ISO) |
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | P80206 (/TAS) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P80206 (/ISO) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | P80206 (/IPI) |
There are 58 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
|
57 |
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
(47 more) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
57 |
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
(47 more) |
Primitive streak formation GO:0090009
The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.
|
57 |
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
(47 more) |
Positive regulation of gastrulation GO:2000543
Any process that activates or increases the frequency, rate or extent of gastrulation.
|
57 |
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
D2GVQ2 (/ISS)
(47 more) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
21 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(11 more) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
20 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(10 more) |
Regulation of smoothened signaling pathway GO:0008589
Any process that modulates the frequency, rate or extent of smoothened signaling.
|
20 |
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
(10 more) |
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
|
20 |
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
(10 more) |
Midbrain development GO:0030901
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
|
20 |
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
(10 more) |
Regulation of fibroblast growth factor receptor signaling pathway GO:0040036
Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
|
20 |
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
(10 more) |
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
20 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(10 more) |
Dopaminergic neuron differentiation GO:0071542
The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
|
20 |
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
P32243 (/IGI)
(10 more) |
Dopaminergic neuron differentiation GO:0071542
The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
|
20 |
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
P32243 (/TAS)
(10 more) |
Cell fate specification involved in pattern specification GO:0060573
The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.
|
8 | Q6E236 (/NAS) Q6E236 (/NAS) Q6E236 (/NAS) Q6E236 (/NAS) Q6E236 (/NAS) Q6E236 (/NAS) Q6E236 (/NAS) Q8JG31 (/NAS) |
Midbrain development GO:0030901
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
|
5 | P80206 (/IGI) Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) |
Retinal pigment epithelium development GO:0003406
The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.
|
4 | Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) |
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
|
4 | Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) |
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
|
4 | Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) |
Midbrain-hindbrain boundary development GO:0030917
The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
|
4 | Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) Q91981 (/IGI) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | F1R982 (/IMP) P80206 (/IMP) Q6NYT9 (/IMP) Q8UUZ5 (/IMP) |
Cellular response to alcohol GO:0097306
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
|
4 | Q91981 (/IDA) Q91981 (/IDA) Q91981 (/IDA) Q91981 (/IDA) |
Circadian regulation of gene expression GO:0032922
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
|
3 | F1R982 (/IMP) Q6NYT9 (/IMP) Q8UUZ5 (/IMP) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | F1R982 (/IGI) Q6NYT9 (/IGI) Q8UUZ5 (/IGI) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | F1R982 (/IPI) Q6NYT9 (/IPI) Q8UUZ5 (/IPI) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q91813 (/IDA) Q91813 (/IDA) |
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
|
1 | P80206 (/IMP) |
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | P80206 (/IDA) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | P80206 (/ISO) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
1 | P80206 (/IMP) |
Endoderm development GO:0007492
The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.
|
1 | P80206 (/IGI) |
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | P80206 (/IMP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | P80206 (/IGI) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | P80206 (/IMP) |
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
1 | P80206 (/IMP) |
Telencephalon regionalization GO:0021978
The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.
|
1 | P80206 (/IMP) |
Metencephalon development GO:0022037
The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.
|
1 | P80206 (/IGI) |
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
1 | P80206 (/IMP) |
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | P80206 (/IMP) |
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
|
1 | P80206 (/IGI) |
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
|
1 | P80206 (/IMP) |
Midbrain development GO:0030901
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
|
1 | P80206 (/IMP) |
Somite rostral/caudal axis specification GO:0032525
The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.
|
1 | P80206 (/IMP) |
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
|
1 | P80206 (/IMP) |
Inner ear morphogenesis GO:0042472
The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
|
1 | P80206 (/IGI) |
Eye photoreceptor cell fate commitment GO:0042706
The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
|
1 | P80206 (/IMP) |
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
|
1 | P80206 (/IMP) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P80206 (/IGI) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P80206 (/ISO) |
Neuron fate commitment GO:0048663
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
|
1 | P80206 (/IMP) |
Neuron fate determination GO:0048664
The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.
|
1 | P80206 (/IMP) |
Oligodendrocyte differentiation GO:0048709
The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
|
1 | P80206 (/IMP) |
Diencephalon morphogenesis GO:0048852
The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
|
1 | P80206 (/IGI) |
Anatomical structure development GO:0048856
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
|
1 | P80206 (/IGI) |
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
1 | P80206 (/ISO) |
Dopaminergic neuron differentiation GO:0071542
The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
|
1 | P80206 (/ISO) |
Primitive streak formation GO:0090009
The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.
|
1 | P80206 (/IMP) |
Cellular response to leukemia inhibitory factor GO:1990830
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
|
1 | P80206 (/IEP) |
Positive regulation of gastrulation GO:2000543
Any process that activates or increases the frequency, rate or extent of gastrulation.
|
1 | P80206 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
21 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(11 more) |
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
|
20 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(10 more) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
20 |
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
P32243 (/IDA)
(10 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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3 | P80206 (/IC) Q91813 (/IC) Q91813 (/IC) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | P80206 (/ISO) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
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1 | P80206 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | P80206 (/IDA) |
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
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1 | P80206 (/ISO) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
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1 | P80206 (/ISO) |