The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 141: TetR family transcriptional regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
13 |
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KS52 (/ISS)
Q9KS52 (/ISS)
Q9KS52 (/ISS)
Q9KS52 (/ISS)
(3 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
12 |
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
(2 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
12 |
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
(2 more) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
12 |
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
(2 more) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
12 |
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
(2 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
P9WMC1 (/IPI)
(2 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
10 | O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) O06169 (/IPI) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
6 | Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
6 | Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
6 | Q9HXW2 (/IDA) Q9HXW2 (/IDA) Q9HXW2 (/IDA) Q9HXW2 (/IDA) Q9HXW2 (/IDA) Q9HXW2 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
32 |
A0R666 (/IMP)
A0R666 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
P9WMC1 (/IMP)
(22 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
13 |
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KR96 (/ISS)
Q9KS52 (/ISS)
Q9KS52 (/ISS)
Q9KS52 (/ISS)
Q9KS52 (/ISS)
(3 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
12 |
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
P9WMC1 (/IDA)
(2 more) |
|
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
|
12 |
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
P9WMC1 (/IEP)
(2 more) |
|
Active evasion of host immune response GO:0042783
Any mechanism of immune avoidance that directly affects the host immune system, e.g. blocking any stage in host MHC class I and II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
10 | O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) O06169 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
12 |
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
P9WMC1 (/HDA)
(2 more) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
12 |
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9HXW2 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
Q9KR96 (/IDA)
(2 more) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
12 |
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9HXW2 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
Q9KR96 (/IPI)
(2 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) P95100 (/HDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
6 | Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) Q9KR96 (/IMP) |
