The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 134: Homeobox protein MSX-1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 23 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
14 |
A1YF16 (/ISS)
A1YF16 (/ISS)
A1YF16 (/ISS)
A1YG93 (/ISS)
A1YG93 (/ISS)
A1YG93 (/ISS)
A2T764 (/ISS)
P35548 (/ISS)
P35548 (/ISS)
P35548 (/ISS)
(4 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
7 | P28360 (/ISA) P28360 (/ISA) P28360 (/ISA) P28360 (/ISA) P35548 (/ISA) P35548 (/ISA) P35548 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
7 | P28360 (/ISM) P28360 (/ISM) P28360 (/ISM) P28360 (/ISM) P35548 (/ISM) P35548 (/ISM) P35548 (/ISM) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
7 | P28360 (/NAS) P28360 (/NAS) P28360 (/NAS) P28360 (/NAS) P35548 (/NAS) P35548 (/NAS) P35548 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P13297 (/IPI) P35548 (/IPI) P35548 (/IPI) P35548 (/IPI) Q03358 (/IPI) Q03358 (/IPI) |
|
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
|
4 | P28360 (/IPI) P28360 (/IPI) P28360 (/IPI) P28360 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
4 | P13297 (/IDA) P35548 (/IDA) P35548 (/IDA) P35548 (/IDA) |
|
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
3 | P13297 (/IMP) Q03358 (/IMP) Q03358 (/IMP) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | P13297 (/IDA) Q03358 (/IDA) Q03358 (/IDA) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | P13297 (/IMP) Q03358 (/IMP) Q03358 (/IMP) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
3 | P13297 (/IDA) Q03358 (/IDA) Q03358 (/IDA) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
3 | P35548 (/ISS) P35548 (/ISS) P35548 (/ISS) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
2 | Q03358 (/IPI) Q03358 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P13297 (/IDA) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P13297 (/IDA) |
|
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
|
1 | P13297 (/ISO) |
|
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | P13297 (/IDA) |
There are 100 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
14 |
A1YF16 (/ISS)
A1YF16 (/ISS)
A1YF16 (/ISS)
A1YG93 (/ISS)
A1YG93 (/ISS)
A1YG93 (/ISS)
A2T764 (/ISS)
P35548 (/ISS)
P35548 (/ISS)
P35548 (/ISS)
(4 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
14 |
A1YF16 (/ISS)
A1YF16 (/ISS)
A1YF16 (/ISS)
A1YG93 (/ISS)
A1YG93 (/ISS)
A1YG93 (/ISS)
A2T764 (/ISS)
P35548 (/ISS)
P35548 (/ISS)
P35548 (/ISS)
(4 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
10 | A1YF16 (/ISS) A1YF16 (/ISS) A1YF16 (/ISS) P35548 (/ISS) P35548 (/ISS) P35548 (/ISS) Q0P5C3 (/ISS) Q0P5C3 (/ISS) Q0P5C3 (/ISS) Q9GK08 (/ISS) |
|
Embryonic nail plate morphogenesis GO:0035880
The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
|
5 | P13297 (/IMP) P28360 (/IMP) P28360 (/IMP) P28360 (/IMP) P28360 (/IMP) |
|
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
|
5 | P13297 (/IMP) P28360 (/IMP) P28360 (/IMP) P28360 (/IMP) P28360 (/IMP) |
|
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
|
5 | P13297 (/IMP) P28360 (/IMP) P28360 (/IMP) P28360 (/IMP) P28360 (/IMP) |
|
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | P13297 (/IDA) P28361 (/IDA) Q03358 (/IDA) Q03358 (/IDA) |
|
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
|
4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
|
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
|
4 | P28360 (/IC) P28360 (/IC) P28360 (/IC) P28360 (/IC) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
|
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
4 | G3V6U7 (/IMP) Q03358 (/IMP) Q03358 (/IMP) Q9QUG0 (/IMP) |
|
Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902255
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
|
4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | P13297 (/IDA) Q03358 (/IDA) Q03358 (/IDA) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | P35548 (/IMP) P35548 (/IMP) P35548 (/IMP) |
|
Epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Signal transduction involved in regulation of gene expression GO:0023019
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Positive regulation of BMP signaling pathway GO:0030513
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Embryonic forelimb morphogenesis GO:0035115
The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Embryonic hindlimb morphogenesis GO:0035116
The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Embryonic nail plate morphogenesis GO:0035880
The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
|
3 | P13297 (/IMP) Q03358 (/IMP) Q03358 (/IMP) |
|
Embryonic digit morphogenesis GO:0042733
The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | P13297 (/IDA) Q03358 (/IDA) Q03358 (/IDA) |
|
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
3 | P13297 (/ISO) Q03358 (/ISO) Q03358 (/ISO) |
|
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Cranial suture morphogenesis GO:0060363
The process in which any suture between cranial bones is generated and organized.
|
3 | P35548 (/TAS) P35548 (/TAS) P35548 (/TAS) |
|
Mammary gland epithelium development GO:0061180
The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
BMP signaling pathway involved in heart development GO:0061312
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
|
3 | P35548 (/ISS) P35548 (/ISS) P35548 (/ISS) |
|
Positive regulation of mesenchymal cell apoptotic process GO:2001055
Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.
|
3 | P13297 (/IGI) Q03358 (/IGI) Q03358 (/IGI) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Chondrocyte development GO:0002063
The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Osteoblast development GO:0002076
The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
|
2 | Q03358 (/IGI) Q03358 (/IGI) |
|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
2 | Q03358 (/IGI) Q03358 (/IGI) |
|
Endochondral bone growth GO:0003416
The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
Pituitary gland development GO:0021983
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
|
2 | G3V6U7 (/IEP) Q9QUG0 (/IEP) |
|
Negative regulation of CREB transcription factor activity GO:0032792
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Wound healing, spreading of epidermal cells GO:0035313
The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
2 | Q03358 (/ISO) Q03358 (/ISO) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Negative regulation of keratinocyte differentiation GO:0045617
Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Positive regulation of timing of catagen GO:0051795
Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Bone trabecula formation GO:0060346
The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Frontal suture morphogenesis GO:0060364
The process in which the frontal suture is generated and organized.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Branching involved in mammary gland duct morphogenesis GO:0060444
The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Enamel mineralization GO:0070166
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
|
2 | Q03358 (/IMP) Q03358 (/IMP) |
|
Cellular response to nicotine GO:0071316
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
|
2 | G3V6U7 (/IEP) Q9QUG0 (/IEP) |
|
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Activation of meiosis GO:0090427
Any process that starts the inactive process of meiosis.
|
2 | Q03358 (/IPI) Q03358 (/IPI) |
|
Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
|
2 | Q03358 (/IDA) Q03358 (/IDA) |
|
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
1 | P13297 (/ISO) |
|
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
1 | P28361 (/TAS) |
|
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
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1 | P13297 (/IMP) |
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Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
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1 | P13297 (/IMP) |
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Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
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1 | P13297 (/IGI) |
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Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
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1 | P13297 (/IGI) |
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Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
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1 | P13297 (/IPI) |
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Mesenchymal cell proliferation GO:0010463
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
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1 | P13297 (/IMP) |
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Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
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1 | P13297 (/ISO) |
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BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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1 | P13297 (/ISO) |
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Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
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1 | P13297 (/IMP) |
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Midbrain development GO:0030901
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
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1 | P13297 (/IMP) |
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Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
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1 | P13297 (/ISO) |
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Embryonic nail plate morphogenesis GO:0035880
The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
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1 | P13297 (/ISO) |
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Middle ear morphogenesis GO:0042474
The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).
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1 | P13297 (/IMP) |
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Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
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1 | P13297 (/ISO) |
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Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
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1 | P13297 (/IGI) |
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Regulation of odontogenesis GO:0042481
Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.
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1 | P13297 (/IGI) |
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Negative regulation of DNA binding GO:0043392
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
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1 | P13297 (/IDA) |
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Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
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1 | P13297 (/IGI) |
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Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
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1 | P13297 (/IMP) |
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Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
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1 | P13297 (/ISO) |
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Negative regulation of striated muscle cell differentiation GO:0051154
Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
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1 | P13297 (/IDA) |
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Negative regulation of striated muscle cell differentiation GO:0051154
Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
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1 | P13297 (/IGI) |
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Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
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1 | P13297 (/IMP) |
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Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
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1 | P13297 (/IGI) |
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Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
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1 | P13297 (/ISO) |
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Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
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1 | P13297 (/IMP) |
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Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
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1 | P13297 (/IMP) |
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Activation of meiosis GO:0090427
Any process that starts the inactive process of meiosis.
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1 | P13297 (/IGI) |
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Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902255
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
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1 | P13297 (/ISO) |
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Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
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1 | P13297 (/IGI) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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4 | P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) P28360 (/IDA) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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3 | P35548 (/IDA) P35548 (/IDA) P35548 (/IDA) |
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Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
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3 | P35548 (/IDA) P35548 (/IDA) P35548 (/IDA) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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2 | Q03358 (/TAS) Q03358 (/TAS) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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2 | Q03358 (/ISO) Q03358 (/ISO) |
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Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
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2 | Q03358 (/ISO) Q03358 (/ISO) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P13297 (/IGI) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P13297 (/ISO) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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1 | P13297 (/ISO) |
