The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1072:

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 A0A0G2JV86 (/IEP) A0A0G2K2A4 (/IEP)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of glial cell proliferation GO:0060252
Any process that activates or increases the rate or extent of glial cell proliferation.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
2 A0A0G2JV86 (/IEP) A0A0G2K2A4 (/IEP)
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
2 A0A0G2JV86 (/IEP) A0A0G2K2A4 (/IEP)
Positive regulation of transforming growth factor beta production GO:0071636
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of neuron death GO:1901216
Any process that activates or increases the frequency, rate or extent of neuron death.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of hepatic stellate cell proliferation GO:1904899
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of hepatic stellate cell activation GO:2000491
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)
Positive regulation of testosterone secretion GO:2000845
Any process that activates or increases the frequency, rate or extent of testosterone secretion.
2 A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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