The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Phosphatase 2C, C-terminal domain suprefamily
".
FunFam 1: protein phosphatase 1B isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
3 | O75688 (/IDA) O75688 (/IDA) O75688 (/IDA) |
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
3 | O75688 (/TAS) O75688 (/TAS) O75688 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | O75688 (/IPI) O75688 (/IPI) O75688 (/IPI) |
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
2 | P36993 (/ISO) P36993 (/ISO) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
7 | C9JIR6 (/IMP) C9JIR6 (/IMP) O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) P36993 (/IMP) P36993 (/IMP) |
N-terminal protein myristoylation GO:0006499
The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.
|
5 | O62830 (/ISS) O75688 (/ISS) O75688 (/ISS) O75688 (/ISS) P35815 (/ISS) |
Negative regulation of interferon-beta production GO:0032688
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
|
4 | O62830 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS) |
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
|
4 | O62830 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS) |
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
|
4 | O62830 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS) |
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
|
4 | O62830 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | O75688 (/TAS) O75688 (/TAS) O75688 (/TAS) |
Negative regulation of interferon-beta production GO:0032688
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
|
3 | O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) |
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
|
3 | O75688 (/IDA) O75688 (/IDA) O75688 (/IDA) |
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
|
3 | O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) |
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
|
3 | O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) |
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
|
3 | O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
2 | O62830 (/ISS) P35815 (/ISS) |
N-terminal protein myristoylation GO:0006499
The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.
|
2 | P36993 (/IDA) P36993 (/IDA) |
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
2 | A7YYD2 (/IMP) Q5U386 (/IMP) |
Negative regulation of interferon-beta production GO:0032688
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
|
2 | P36993 (/ISO) P36993 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | O75688 (/IDA) O75688 (/IDA) O75688 (/IDA) P36993 (/IDA) P36993 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | O62830 (/ISS) O75688 (/ISS) O75688 (/ISS) O75688 (/ISS) P35815 (/ISS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
5 | O62830 (/ISS) O75688 (/ISS) O75688 (/ISS) O75688 (/ISS) P35815 (/ISS) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
3 | O75688 (/IDA) O75688 (/IDA) O75688 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | O75688 (/TAS) O75688 (/TAS) O75688 (/TAS) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P36993 (/ISO) P36993 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | P36993 (/IDA) P36993 (/IDA) |