CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 99: Two-component system response regulator TorR
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
24 |
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
(14 more) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
15 |
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
(5 more) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
10 | P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) P07545 (/TAS) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
7 | Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
5 | Q9HWS7 (/IDA) Q9HWS7 (/IDA) Q9HWS7 (/IDA) Q9HWS7 (/IDA) Q9HWS7 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
2 | Q883X4 (/IMP) Q8EHJ3 (/IMP) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
2 | Q883X4 (/IMP) Q8EHJ3 (/IMP) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
1 | Q8EHJ3 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
1 | Q8EHJ3 (/IPI) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
1 | Q8EHJ3 (/IDA) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
1 | Q8EHJ3 (/IPI) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
1 | Q8EHJ3 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
1 | Q8EHJ3 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
24 |
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
P38684 (/IDA)
(14 more) |
|
Positive regulation of glucose transmembrane transport GO:0010828
Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
22 |
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
G3XCY6 (/IMP)
(12 more) |
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
15 |
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KRC3 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
(5 more) |
|
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
|
7 | Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) |
|
Positive regulation of single-species biofilm formation on inanimate substrate GO:1900233
Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
|
5 | Q9HWS7 (/IMP) Q9HWS7 (/IMP) Q9HWS7 (/IMP) Q9HWS7 (/IMP) Q9HWS7 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q883X4 (/EXP) Q8EHJ3 (/EXP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q883X4 (/EXP) Q8EHJ3 (/EXP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q883X4 (/IEP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q883X4 (/IEP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
2 | Q883X4 (/IMP) Q8EHJ3 (/IMP) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
1 | Q8EHJ3 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
1 | Q8EHJ3 (/IPI) |
