CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 77: DNA-binding transcriptional regulator CpxR
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
224 |
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
A0A0H3NK16 (/IPI)
(214 more) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
131 |
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
(121 more) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
8 | Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of cell-substrate adhesion GO:0010810
Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
|
131 |
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
P0AE88 (/IMP)
(121 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
131 |
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
(121 more) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
131 |
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
(121 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) Q9KNN9 (/ISS) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q7VLH6 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
131 |
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
P0AE88 (/IDA)
(121 more) |
