The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 67: Iron-dependent repressor IdeR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI) P9WMH1 (/IPI)
(2 more)
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Cadmium ion binding GO:0046870
Interacting selectively and non-covalently with cadmium (Cd) ions.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
2 P0DJL7 (/IMP) P0DJL7 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P0DJL7 (/IMP) P0DJL7 (/IMP)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
12 P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI) P9WMH1 (/IGI)
(2 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
12 P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP)
(2 more)
Siderophore biosynthetic process from catechol GO:0019540
The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol.
12 P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP) P9WMH1 (/IMP)
(2 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
12 P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA) P9WMH1 (/IDA)
(2 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
2 P0DJL7 (/IMP) P0DJL7 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA) P9WMH1 (/HDA)
(2 more)
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