The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 528: Transcriptional regulatory protein EmbR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
14 O05797 (/IDA) O05797 (/IDA) O05797 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA)
(4 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
11 P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA)
(1 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
11 P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA)
(1 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
11 P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA) P9WGJ9 (/IDA)
(1 more)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
6 O53145 (/IDA) O53145 (/IDA) O53145 (/IDA) O53145 (/IDA) O53145 (/IDA) O53145 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
3 O05797 (/IEP) O05797 (/IEP) O05797 (/IEP)
Molybdopterin cofactor biosynthetic process GO:0032324
The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
3 O05797 (/IEP) O05797 (/IEP) O05797 (/IEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA) P9WGJ9 (/HDA)
(1 more)
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