CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 30: Forkhead box protein K2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 47 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
9 | Q01167 (/NAS) Q66IG8 (/NAS) Q708W1 (/NAS) Q708W1 (/NAS) Q708W2 (/NAS) Q708W2 (/NAS) Q7ZX03 (/NAS) Q92949 (/NAS) Q92949 (/NAS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
8 | Q66IG8 (/NAS) Q708W1 (/NAS) Q708W1 (/NAS) Q708W2 (/NAS) Q708W2 (/NAS) Q7ZX03 (/NAS) Q92949 (/NAS) Q92949 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P41813 (/IPI) P42128 (/IPI) P85037 (/IPI) Q01167 (/IPI) Q3UCQ1 (/IPI) Q92949 (/IPI) Q92949 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
5 | F1QDF8 (/IDA) P40466 (/IDA) P41813 (/IDA) P42128 (/IDA) Q01167 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
4 | P85037 (/IDA) Q01167 (/IDA) Q92949 (/IDA) Q92949 (/IDA) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
4 | O60129 (/IDA) P40466 (/IDA) Q01167 (/IDA) Q61660 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | P85037 (/ISA) Q01167 (/ISA) Q92949 (/ISA) Q92949 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | P85037 (/ISM) Q01167 (/ISM) Q92949 (/ISM) Q92949 (/ISM) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | O60129 (/IDA) P40466 (/IDA) Q01167 (/IDA) Q61660 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
3 | P42128 (/ISO) Q3UCQ1 (/ISO) Q61660 (/ISO) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | P40466 (/IDA) P85037 (/IDA) Q3UCQ1 (/IDA) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | Q63247 (/ISS) Q92949 (/ISS) Q92949 (/ISS) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
2 | Q3UCQ1 (/ISS) Q7ZX03 (/ISS) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
2 | Q3UCQ1 (/ISS) Q7ZX03 (/ISS) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | O60129 (/IDA) P42128 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | O14270 (/NAS) Q01167 (/NAS) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | P40466 (/IDA) P41813 (/IDA) |
|
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
2 | P40466 (/IDA) P41813 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | P40466 (/HDA) P41813 (/HDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | Q3UCQ1 (/ISS) Q7ZX03 (/ISS) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | Q01167 (/IDA) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | Q3UCQ1 (/ISO) |
|
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
1 | P42128 (/IDA) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
1 | O14270 (/ISM) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
1 | Q3UCQ1 (/ISO) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | P41813 (/IDA) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | P41813 (/IGI) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | P41813 (/IMP) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P40466 (/IGI) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | O60129 (/IMP) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P42128 (/ISO) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P40466 (/IGI) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | O60129 (/IMP) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q3UCQ1 (/ISO) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P42128 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | Q5A7S7 (/IMP) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | P42128 (/ISO) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
1 | P41813 (/IDA) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
1 | P41813 (/IMP) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | P41813 (/IDA) |
|
Centromeric DNA binding GO:0019237
Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.
|
1 | P40466 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q3UCQ1 (/ISO) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | P85037 (/IPI) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | P42128 (/ISO) |
There are 132 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
10 | Q32NH9 (/ISS) Q5M7N6 (/ISS) Q63247 (/ISS) Q66IG8 (/ISS) Q708W1 (/ISS) Q708W1 (/ISS) Q708W2 (/ISS) Q708W2 (/ISS) Q92949 (/ISS) Q92949 (/ISS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | Q01167 (/NAS) Q66IG8 (/NAS) Q708W1 (/NAS) Q708W1 (/NAS) Q708W2 (/NAS) Q708W2 (/NAS) Q7ZX03 (/NAS) |
|
Midgut development GO:0007494
The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.
|
6 | A0JL24 (/IMP) M9PC64 (/IMP) M9PF47 (/IMP) M9PI07 (/IMP) Q0E8F8 (/IMP) Q8IQE9 (/IMP) |
|
Visceral mesoderm-endoderm interaction involved in midgut development GO:0007495
The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.
|
6 | A0JL24 (/IMP) M9PC64 (/IMP) M9PF47 (/IMP) M9PI07 (/IMP) Q0E8F8 (/IMP) Q8IQE9 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
6 | A0JL24 (/IMP) M9PC64 (/IMP) M9PF47 (/IMP) M9PI07 (/IMP) Q0E8F8 (/IMP) Q8IQE9 (/IMP) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
6 | A0JL24 (/IMP) M9PC64 (/IMP) M9PF47 (/IMP) M9PI07 (/IMP) Q0E8F8 (/IMP) Q8IQE9 (/IMP) |
|
Cellular response to virus GO:0098586
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
6 | A0JL24 (/IMP) M9PC64 (/IMP) M9PF47 (/IMP) M9PI07 (/IMP) Q0E8F8 (/IMP) Q8IQE9 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | P42128 (/IDA) P85037 (/IDA) Q01167 (/IDA) Q3UCQ1 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | P42128 (/IDA) P85037 (/IDA) Q01167 (/IDA) Q3UCQ1 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | Q01167 (/IDA) Q61660 (/IDA) Q92949 (/IDA) Q92949 (/IDA) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
3 | O60129 (/IMP) P40466 (/IMP) P41813 (/IMP) |
|
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
|
3 | F1QDF8 (/IMP) F1R8Z9 (/IMP) Q61660 (/IMP) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
3 | F1QDF8 (/IMP) F1R8Z9 (/IMP) Q61660 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Cellular glucose homeostasis GO:0001678
A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Cellular glucose homeostasis GO:0001678
A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
2 | F1QDF8 (/IMP) F1R8Z9 (/IMP) |
|
Central tolerance induction GO:0002508
Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Negative regulation of germinal center formation GO:0002635
Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Positive regulation of central B cell tolerance induction GO:0002897
Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Negative regulation of humoral immune response mediated by circulating immunoglobulin GO:0002924
Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Heart jogging GO:0003146
The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
|
2 | F1QDF8 (/IMP) F1R8Z9 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | P40466 (/IGI) P41813 (/IGI) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | O60129 (/IMP) Q5A7S7 (/IMP) |
|
Humoral immune response GO:0006959
An immune response mediated through a body fluid.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | Q92949 (/NAS) Q92949 (/NAS) |
|
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
2 | Q92949 (/NAS) Q92949 (/NAS) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
2 | P85037 (/TAS) Q01167 (/TAS) |
|
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Positive regulation of DNA-dependent DNA replication initiation GO:0032298
Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.
|
2 | P40466 (/IMP) P41813 (/IMP) |
|
Negative regulation of T cell differentiation in thymus GO:0033085
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Establishment of apical/basal cell polarity GO:0035089
The specification and formation of the polarity of a cell along its apical/basal axis.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Metanephric part of ureteric bud development GO:0035502
The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.
|
2 | Q92949 (/IEP) Q92949 (/IEP) |
|
Regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter GO:0035947
Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter GO:0035947
Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Negative regulation of interleukin-6 biosynthetic process GO:0045409
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P42128 (/ISO) Q3UCQ1 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P42128 (/ISO) Q3UCQ1 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q63247 (/ISS) Q7ZX03 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q3UCQ1 (/ISO) Q61660 (/ISO) |
|
Negative regulation of B cell activation GO:0050869
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Lung epithelium development GO:0060428
The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
|
2 | Q92949 (/IEP) Q92949 (/IEP) |
|
Lung epithelium development GO:0060428
The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
|
2 | Q92949 (/NAS) Q92949 (/NAS) |
|
Epithelium development GO:0060429
The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
|
2 | Q01167 (/ISS) Q7ZX03 (/ISS) |
|
Negative regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071930
Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle.
|
2 | P40466 (/IGI) P41813 (/IGI) |
|
Glomerular parietal epithelial cell development GO:0072016
The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
|
2 | Q92949 (/IEP) Q92949 (/IEP) |
|
Positive regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090282
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
|
2 | P40466 (/IGI) P41813 (/IGI) |
|
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
2 | Q92949 (/ISS) Q92949 (/ISS) |
|
Positive regulation of lung ciliated cell differentiation GO:1901248
Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.
|
2 | Q92949 (/IDA) Q92949 (/IDA) |
|
Positive regulation of DNA replication initiation GO:1903468
Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
|
2 | P40466 (/IMP) P41813 (/IMP) |
|
Negative regulation of pseudohyphal growth GO:2000221
Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.
|
2 | P40466 (/IGI) P41813 (/IGI) |
|
Negative regulation of pseudohyphal growth GO:2000221
Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.
|
2 | P41813 (/IMP) Q5A7S7 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q61660 (/IMP) |
|
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
1 | Q5A7S7 (/IMP) |
|
Cellular glucose homeostasis GO:0001678
A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.
|
1 | P42128 (/ISO) |
|
Central tolerance induction GO:0002508
Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
|
1 | Q61660 (/IMP) |
|
Negative regulation of germinal center formation GO:0002635
Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.
|
1 | Q61660 (/IMP) |
|
Positive regulation of central B cell tolerance induction GO:0002897
Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
|
1 | Q61660 (/IMP) |
|
Negative regulation of humoral immune response mediated by circulating immunoglobulin GO:0002924
Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
|
1 | Q61660 (/IMP) |
|
Epithelial cilium movement involved in extracellular fluid movement GO:0003351
The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.
|
1 | F1QDF8 (/IMP) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | P42128 (/IDA) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | O14270 (/NAS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q01167 (/TAS) |
|
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
|
1 | P40466 (/IGI) |
|
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
|
1 | P40466 (/IMP) |
|
Humoral immune response GO:0006959
An immune response mediated through a body fluid.
|
1 | Q61660 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q63247 (/IEP) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | Q61660 (/IEP) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q61660 (/IMP) |
|
Donor selection GO:0007535
The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
|
1 | P40466 (/IGI) |
|
Donor selection GO:0007535
The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
|
1 | P40466 (/IMP) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | F1QDF8 (/IMP) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | P42128 (/ISO) |
|
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
1 | P42128 (/ISO) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | Q63247 (/IEP) |
|
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q61660 (/IMP) |
|
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q5A7S7 (/IMP) |
|
Regulation of epithelial cell differentiation GO:0030856
Any process that modulates the frequency, rate or extent of epithelial cell differentiation.
|
1 | Q61660 (/IDA) |
|
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
|
1 | P40466 (/IMP) |
|
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
1 | Q61660 (/IMP) |
|
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | Q63247 (/IEP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | P41813 (/IGI) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | P41813 (/IMP) |
|
Negative regulation of T cell differentiation in thymus GO:0033085
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
|
1 | Q61660 (/IMP) |
|
Negative regulation of transcription elongation from RNA polymerase II promoter GO:0034244
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | P40466 (/IGI) |
|
Negative regulation of transcription elongation from RNA polymerase II promoter GO:0034244
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | P40466 (/IMP) |
|
Establishment of apical/basal cell polarity GO:0035089
The specification and formation of the polarity of a cell along its apical/basal axis.
|
1 | Q61660 (/IMP) |
|
Regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter GO:0035947
Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.
|
1 | P42128 (/ISO) |
|
Negative regulation of T cell proliferation GO:0042130
Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
|
1 | Q61660 (/IMP) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
1 | P42128 (/ISO) |
|
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q5A7S7 (/IMP) |
|
Motile cilium assembly GO:0044458
The aggregation, arrangement and bonding together of a set of components to form a motile cilium.
|
1 | Q61660 (/IGI) |
|
Motile cilium assembly GO:0044458
The aggregation, arrangement and bonding together of a set of components to form a motile cilium.
|
1 | Q61660 (/IMP) |
|
Negative regulation of interleukin-6 biosynthetic process GO:0045409
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
|
1 | Q61660 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q7ZX03 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q61660 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O60129 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q63247 (/ISS) |
|
Negative regulation of B cell activation GO:0050869
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
|
1 | Q61660 (/IMP) |
|
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
|
1 | Q61660 (/IMP) |
|
Regulation of meiotic cell cycle GO:0051445
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
|
1 | O60129 (/IMP) |
|
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
|
1 | F1R8Z9 (/IMP) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
1 | F1QDF8 (/IDA) |
|
Regulation of cilium beat frequency involved in ciliary motility GO:0060296
Any process that modulates the frequency of cilium beating involved in ciliary motility.
|
1 | F1QDF8 (/IMP) |
|
Epithelium development GO:0060429
The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
|
1 | Q61660 (/IEP) |
|
Left/right pattern formation GO:0060972
The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
|
1 | Q61660 (/IMP) |
|
Negative regulation of chromatin silencing at silent mating-type cassette GO:0061186
Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
|
1 | P41813 (/IGI) |
|
Negative regulation of chromatin silencing at silent mating-type cassette GO:0061186
Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
|
1 | P41813 (/IMP) |
|
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
|
1 | P42128 (/ISO) |
|
Cellular response to methylmercury GO:0071406
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
|
1 | P40466 (/IGI) |
|
Cellular response to methylmercury GO:0071406
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
|
1 | P40466 (/IMP) |
|
Positive regulation of chromatin silencing at silent mating-type cassette GO:0090055
Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
|
1 | P40466 (/IGI) |
|
Positive regulation of chromatin silencing at silent mating-type cassette GO:0090055
Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
|
1 | P40466 (/IMP) |
|
Positive regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090282
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
|
1 | P41813 (/IMP) |
|
Negative regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090419
Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
|
1 | P41813 (/IGI) |
|
Negative regulation of transcription involved in G2/M transition of mitotic cell cycle GO:0090419
Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
|
1 | P40466 (/IMP) |
|
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | Q61660 (/IDA) |
|
Positive regulation of induction of conjugation with cellular fusion GO:1900237
Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion.
|
1 | O60129 (/IMP) |
|
Positive regulation of lung ciliated cell differentiation GO:1901248
Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.
|
1 | Q61660 (/ISO) |
|
Cellular response to insulin-like growth factor stimulus GO:1990314
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
|
1 | Q63247 (/IEP) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | O60129 (/IDA) P40466 (/IDA) P41813 (/IDA) P85037 (/IDA) Q01167 (/IDA) Q3UCQ1 (/IDA) Q5A7S7 (/IDA) Q61660 (/IDA) Q92949 (/IDA) Q92949 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | Q32NH9 (/ISS) Q5M7N6 (/ISS) Q63247 (/ISS) Q66IG8 (/ISS) Q708W1 (/ISS) Q708W1 (/ISS) Q708W2 (/ISS) Q708W2 (/ISS) Q7ZX03 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | Q66IG8 (/NAS) Q708W1 (/NAS) Q708W1 (/NAS) Q708W2 (/NAS) Q708W2 (/NAS) Q7ZX03 (/NAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P42128 (/ISO) Q3UCQ1 (/ISO) Q61660 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | O14270 (/HDA) O60129 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P42128 (/IC) Q01167 (/IC) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | P85037 (/TAS) Q01167 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P85037 (/IDA) Q3UCQ1 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P40466 (/IDA) P41813 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | O60129 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P42128 (/ISO) |
|
M/G1 phase-specific MADS box-forkhead transcription factor complex GO:0097221
A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.
|
1 | O60129 (/IDA) |
