CATH Domain 6qhcB02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	kallikrein-6 isoform X1

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt Q92876

UniProtKB Entries (1)

KLK6_HUMAN

Homo sapiens

Kallikrein-6

PDB Structure

PDB	6QHC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome. White, G.V., Edgar, E.V., Holmes, D.S., Lewell, X.Q., Liddle, J., Polyakova, O., Smith, K.J., Thorpe, J.H., Walker, A.L., Wang, Y., Young, R.J., Hovnanian, A. Bioorg. Med. Chem. Lett.