CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family tRNA (Adenine(22)-N(1))-methyltransferase TrmK

Enzyme Information

2.1.1.217
tRNA (adenine(22)-N(1))-methyltransferase.
based on mapping to UniProt P54471
S-adenosyl-L-methionine + adenine(22) in tRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(22) in tRNA.
-!- The enzyme specifically methylates adenine(22) in tRNA. -!- Formerly EC 2.1.1.36.

UniProtKB Entries (1)

P54471
TRMK_BACSU
Bacillus subtilis subsp. subtilis str. 168
TRNA (adenine(22)-N(1))-methyltransferase

PDB Structure

PDB 6Q56
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Degut, C., Roovers, M., Barraud, P., Brachet, F., Feller, A., Larue, V., Al Refaii, A., Caillet, J., Droogmans, L., Tisne, C.
Nucleic Acids Res.