CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.920 | Metal Transport, Frataxin; Chain A |
|
3.30.920.10 | Frataxin/CyaY |
Domain Context
CATH Clusters
| Superfamily | Frataxin/CyaY |
| Functional Family | Frataxin, mitochondrial |
Enzyme Information
| 1.16.3.1 |
Ferroxidase.
based on mapping to UniProt Q16595
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.
|
UniProtKB Entries (1)
| Q9H1K1 |
ISCU_HUMAN
Homo sapiens
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
|
PDB Structure
| PDB | 6NZU |
| External Links | |
| Method | ELECTRON MICROSCOPY |
| Organism | |
| Primary Citation |
Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
Nat Commun
|