CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.230 | Ribosomal Protein S5; domain 2 |
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3.30.230.20 | lpxc deacetylase, domain 1 |
Domain Context
CATH Clusters
Superfamily | lpxc deacetylase, domain 1 |
Functional Family |
Enzyme Information
3.5.1.108 |
UDP-3-O-acyl-N-acetylglucosamine deacetylase.
based on mapping to UniProt O67648
UDP-3-O-((3R)-3-hydroxytetradecanoyl)-N-acetyl-alpha-D-glucosamine + H(2)O = UDP-3-O-((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + acetate.
-!- The enzyme catalyzes a committed step in the biosynthesis of lipid A. -!- Formerly EC 3.5.1.n1.
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UniProtKB Entries (1)
O67648 |
LPXC_AQUAE
Aquifex aeolicus VF5
UDP-3-O-acyl-N-acetylglucosamine deacetylase
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PDB Structure
PDB | 6IH0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Aquifex aeolicus LpxC complex with ACHN-975
To Be Published
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