CATH Classification

Domain Context

CATH Clusters

Superfamily lpxc deacetylase, domain 1
Functional Family

Enzyme Information

3.5.1.108
UDP-3-O-acyl-N-acetylglucosamine deacetylase.
based on mapping to UniProt O67648
UDP-3-O-((3R)-3-hydroxytetradecanoyl)-N-acetyl-alpha-D-glucosamine + H(2)O = UDP-3-O-((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + acetate.
-!- The enzyme catalyzes a committed step in the biosynthesis of lipid A. -!- Formerly EC 3.5.1.n1.

UniProtKB Entries (1)

O67648
LPXC_AQUAE
Aquifex aeolicus VF5
UDP-3-O-acyl-N-acetylglucosamine deacetylase

PDB Structure

PDB 6IH0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Aquifex aeolicus LpxC complex with ACHN-975
Li, D.Y., Fan, S., Jin, Y.Y., Zhang, C., Lv, G.X., Wu, G.T., Yang, Z.Y.
To Be Published
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