CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1170 | MutS, DNA mismatch repair protein, domain I |
|
3.40.1170.60 |
Domain Context
CATH Clusters
| Superfamily | 3.40.1170.60 |
| Functional Family | DNA polymerase IV |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q47155
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
| Q47155 |
DPO4_ECOLI
Escherichia coli K-12
DNA polymerase IV
|
PDB Structure
| PDB | 6IG1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction.
Nucleic Acids Res.
|
