CATH Domain 6hlsE01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1340	Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1
	3.40.1340.10	RNA polymerase, Rpb5, N-terminal domain

Domain Context

CATH Clusters

Superfamily	RNA polymerase, Rpb5, N-terminal domain
Functional Family	DNA-directed RNA polymerases I, II, and III subunit RPABC1

Enzyme Information

UniProtKB Entries (1)

RPA1_YEAST

Saccharomyces cerevisiae S288C

DNA-directed RNA polymerase I subunit RPA190

PDB Structure

PDB	6HLS
External Links	PDBSum Proteopedia
Method	ELECTRON MICROSCOPY
Organism
Primary Citation	The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Tafur, L., Sadian, Y., Hanske, J., Wetzel, R., Weis, F., Muller, C.W. Elife