CATH Domain 6h9xA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Serine--tRNA ligase

Enzyme Information

6.1.1.11

Serine--tRNA ligase.

based on mapping to UniProt W9BNU9

(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).

-!- This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.

UniProtKB Entries (1)

W9BNU9

W9BNU9_KLEPN

Klebsiella pneumoniae

Serine--tRNA ligase

PDB Structure

PDB	6H9X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily. De Ruysscher, D., Pang, L., De Graef, S., Nautiyal, M., De Borggraeve, W.M., Rozenski, J., Strelkov, S.V., Weeks, S.D., Van Aerschot, A. Eur.J.Med.Chem.