CATH Classification
Domain Context
CATH Clusters
Superfamily | Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 |
Functional Family | Alkylglycerone-phosphate synthase |
Enzyme Information
2.5.1.26 |
Alkylglycerone-phosphate synthase.
based on mapping to UniProt P97275
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
-!- The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.
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UniProtKB Entries (1)
P97275 |
ADAS_CAVPO
Cavia porcellus
Alkyldihydroxyacetonephosphate synthase, peroxisomal
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PDB Structure
PDB | 6GOU |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.
Eur J Med Chem
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