CATH Domain 6girA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Seryl-tRNA synthetase, cytoplasmic

Enzyme Information

6.1.1.11

Serine--tRNA ligase.

based on mapping to UniProt Q39230

(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).

-!- This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.

UniProtKB Entries (1)

Q39230

SYSC_ARATH

Arabidopsis thaliana

Serine--tRNA ligase, cytoplasmic

PDB Structure

PDB	6GIR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Arabidopsis seryl-tRNA synthetase: the first crystal structure and novel protein interactor of plant aminoacyl-tRNA synthetase. Kekez, M., Zanki, V., Kekez, I., Baranasic, J., Hodnik, V., Duchene, A.M., Anderluh, G., Gruic-Sovulj, I., Matkovic-Calogovic, D., Weygand-Durasevic, I., Rokov-Plavec, J. FEBS J.