CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P35030
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P05067
A4_HUMAN
Homo sapiens
Amyloid-beta precursor protein

PDB Structure

PDB 6GFI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries.
Naftaly, S., Cohen, I., Shahar, A., Hockla, A., Radisky, E.S., Papo, N.
Nat Commun
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