CATH Classification

Domain Context

CATH Clusters

Superfamily Cysteine proteinases
Functional Family Cruzipain

Enzyme Information

UniProtKB Entries (1)

Q95PM0
Q95PM0_TRYBR
Trypanosoma brucei rhodesiense
Cysteine protease

PDB Structure

PDB 6EXQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
Giroud, M., Dietzel, U., Anselm, L., Banner, D., Kuglstatter, A., Benz, J., Blanc, J.B., Gaufreteau, D., Liu, H., Lin, X., Stich, A., Kuhn, B., Schuler, F., Kaiser, M., Brun, R., Schirmeister, T., Kisker, C., Diederich, F., Haap, W.
J. Med. Chem.