CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.70 | Cathepsin B; Chain A | |
3.90.70.10 | Cysteine proteinases |
Domain Context
CATH Clusters
Superfamily | Cysteine proteinases |
Functional Family | Cruzipain |
Enzyme Information
UniProtKB Entries (1)
Q95PM0 |
Q95PM0_TRYBR
Trypanosoma brucei rhodesiense
Cysteine protease
|
PDB Structure
PDB | 6EXO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
J. Med. Chem.
|